Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302498 | 0.88 | NPC1 (0.33) | NPC1RAB9AEGLN2EGLN1 | |
| SCHEMBL7148633 | 0.87 | CNR2 (0.38) | — | |
| SCHEMBL5643802 | 0.87 | NPC1 (0.35) | NPC1RAB9A | |
| SCHEMBL7142405 | 0.85 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL7149442 | 0.85 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7142425 | 0.82 | POLB (0.33) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7570384 | 0.81 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23636595 | 0.78 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6855342 | 0.77 | DYRK1A (0.36) | SMN1; SMN2 | |
| SCHEMBL7787074 | 0.76 | CYP1A2 (0.38) | NPC1RAB9AEGLN2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515051-B2 | Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6458872-B1 | FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-07-25 | — | — | US | disclosed |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | disclosed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-20010007886-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2001-07-12 | — | — | US | disclosed |
| US-6166218-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-5977219-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | NPC1 2921/4885RAB9A 4813/4885SMN1; SMN2 2440/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | NPC1 2921/4885RAB9A 4813/4885SMN1; SMN2 2440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.