Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142405 | 0.93 | NPC1 (0.32) | NPC1RAB9A | |
| SCHEMBL7148631 | 0.88 | NPC1 (0.32) | NPC1RAB9AEGLN2EGLN1 | |
| SCHEMBL9302503 | 0.86 | CNR1 (0.34) | NPC1RAB9A | |
| SCHEMBL29371482 | 0.86 | NPC1 (0.44) | NPC1RAB9AIDH1POLBLMNA | |
| SCHEMBL673358 | 0.86 | NPC1 (0.44) | NPC1RAB9AIDH1POLBLMNA | |
| SCHEMBL7787074 | 0.84 | CYP1A2 (0.38) | NPC1RAB9AEGLN2EGLN1POLB | |
| SCHEMBL8958781 | 0.82 | NPC1 (0.35) | NPC1RAB9AEGLN2EGLN1POLB | |
| SCHEMBL7142407 | 0.82 | CNR1 (0.32) | — | |
| SCHEMBL7143461 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL22164129 | 0.81 | NPC1 (0.37) | NPC1RAB9APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5278314-A | N-Phenol-substituted benzotriazoles | CIBA-GEIGY CORPORATION (US) | 1994-01-11 | — | — | US | claimed |
| EP-0576527-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | Ciba SC Holding AG (CH) | 1994-01-05 | — | — | EP | claimed |
| WO-1992014718-A1 | 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA-GEIGY AG (CH) | 1992-09-03 | — | — | WO | claimed |