Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.39 |
| ▸ | GABRD | O14764 | 3/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.39 |
| ▸ | GABRE | P78334 | 3/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151198 | 0.90 | GABRP (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2586587 | 0.85 | ALDH1A1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL294836 | 0.84 | CYP1A2 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2498889 | 0.76 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31668786 | 0.75 | SELL (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28733643 | 0.75 | GABRP (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL542401 | 0.75 | SELL (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27364912 | 0.73 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8743511 | 0.73 | GABRP (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8772723 | 0.73 | MCL1 (0.47) | KDM4APPARASELLSELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620864-B2 | With a plasticizer, a catalyst for hardening by ring opening, a catalyst for hardening by light and as accelerator a p-aminobenzoic acid alkyl ester, N,N-disubstituted by hydroxyalkyl groups; free of contraction and adhesiveness | LSP DENTAL CHEMISTRY AG (CH) | 2003-09-16 | — | — | US | claimed |
| US-20020040103-A1 | Epoxy compounds for use in dental medicine and/or dentistry | LSP DENTAL CHEMISTRY AG (CH) | 2002-04-04 | — | — | US | claimed |
| US-6620864-B2 | With a plasticizer, a catalyst for hardening by ring opening, a catalyst for hardening by light and as accelerator a p-aminobenzoic acid alkyl ester, N,N-disubstituted by hydroxyalkyl groups; free of contraction and adhesiveness | LSP DENTAL CHEMISTRY AG (CH) | 2003-09-16 | — | — | US | disclosed |
| US-20020040103-A1 | Epoxy compounds for use in dental medicine and/or dentistry | LSP DENTAL CHEMISTRY AG (CH) | 2002-04-04 | — | — | US | disclosed |