Succinic Acid

Succinic Acid

SCHEMBL7149007

NCC(N)CO.O=C(O)CCC(=O)O.O=C(O)CCC(=O)O

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4

The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.37
LMNA P02545 4/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.45
EGLN1 Q9GZT9 1/20 0.45
GABRR1 P24046 4/20 0.44
ENPEP Q07075 6/20 0.43
ANPEP P15144 3/20 0.43
GABRP O00591 3/20 0.41
GABRD O14764 3/20 0.41
GABRA1 P14867 3/20 0.41
GABRB1 P18505 3/20 0.41
GABRG2 P18507 3/20 0.41
GABRB3 P28472 3/20 0.41
GABRA5 P31644 3/20 0.41
GABRA3 P34903 3/20 0.41
GABRA2 P47869 3/20 0.41
GABRB2 P47870 3/20 0.41
GABRA4 P48169 3/20 0.41
GABRE P78334 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL22346000 0.87 LMNA (0.53) LMNAALKBH5SUCNR1EGLN1GABRR1
Acetic Acid SCHEMBL10583204 0.82 FFAR3 (0.37) LMNAGABRR1ENPEPGABRPGABRD
SCHEMBL8674278 0.81 ALDH1A1 (0.35) ANPEPTSHRALDH1A1
SCHEMBL125861 0.81
SCHEMBL4538111 0.81
SCHEMBL4633342 0.81
Hydrochloric Acid SCHEMBL9709009 0.78
Hydrochloric Acid SCHEMBL5310524 0.78
Hydrochloric Acid SCHEMBL9709014 0.78
Succinic Acid SCHEMBL6818560 0.78 ENPEP (0.48) LMNAGABRR1ENPEPANPEPGABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995029220-A1 DETERGENT COMPOSITIONS CONTAINING DIAMINE TETRACARBOXYLIC ACID OR SALTS THEREOF THE PROCTER & GAMBLE COMPANY (US) 1995-11-02 WO claimed
EP-3727307-A1 METHOD AND APPARATUS FOR DYEING HAIR FIBRES USING RADIO FREQUENCY ELECTROMAGNETIC RADIATION Jemella Limited (GB) 2020-10-28 EP disclosed
EP-3155435-A1 SYSTEM AND METHODS OF DETECTING AND DEMONSTRATING ULTRAVIOLET DAMAGE TO HAIR VIA EVALUATION OF PROTEIN FRAGMENTS The Procter & Gamble Company (US) 2017-04-19 EP disclosed
WO-2015191343-A1 SYSTEM AND METHODS OF DETECTING AND DEMONSTRATING ULTRAVIOLET DAMAGE TO HAIR VIA EVALUATION OF PROTEIN FRAGMENTS THE PROCTER & GAMBLE COMPANY (US) 2015-12-17 WO disclosed
EP-1330511-A2 DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-07-30 EP disclosed
WO-2002055644-A2 DETERGENT COMPOSITIONS PROCTER & GAMBLE (US) 2002-07-18 WO disclosed
EP-0991747-A1 PHOSPHATE-FREE DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-04-12 EP disclosed
EP-0991747-A4 PHOSPHATE-FREE DETERGENT COMPOSITIONS PROCTER & GAMBLE (US) 2000-04-12 EP disclosed
WO-1998004775-A1 USE OF COMPLEXING AGENTS FOR CELLULOSE AND WOOD BLEACHING, PAPER PRODUCTION AND USED PAPER DEINKING BASF AKTIENGESELLSCHAFT (DE) 1998-02-05 WO disclosed
WO-1997020907-A1 PHOSPHATE-FREE DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-06-12 WO disclosed
WO-1995029220-A1 DETERGENT COMPOSITIONS CONTAINING DIAMINE TETRACARBOXYLIC ACID OR SALTS THEREOF THE PROCTER & GAMBLE COMPANY (US) 1995-11-02 WO disclosed