Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29425757 | 1.00 | — | — | |
| Bicarbonate SCHEMBL15334108 | 0.93 | — | — | |
| Bicarbonate SCHEMBL7697493 | 0.93 | CA1 (0.71) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL6763630 | 0.93 | — | — | |
| Bicarbonate SCHEMBL29432629 | 0.93 | — | — | |
| Bicarbonate SCHEMBL6478072 | 0.91 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL570721 | 0.91 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL1179 | 0.91 | — | — | |
| Bicarbonate SCHEMBL15271537 | 0.91 | — | — | |
| Bicarbonate SCHEMBL570968 | 0.91 | CA1 (1.00) | CA1CA2CA9FFAR3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250057161-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | ADAMA MAKHTESHIM LTD. (IL) | 2025-02-20 | — | — | US | disclosed |
| US-12127559-B2 | Use of cyclodextrins as agrochemical delivery system | ADAMA MAKHTESHIM LTD. (IL) | 2024-10-29 | — | — | US | disclosed |
| WO-2024143387-A1 | ADSORPTION AGENT | 東洋紡株式会社 | 2024-07-04 | — | — | WO | disclosed |
| CN-116500186-A | Analysis and test method for sulfate content in desulfurized gypsum | 中电华创电力技术研究有限公司 | 2023-07-28 | — | — | CN | disclosed |
| US-20210386067-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | ADAMA MAKHTESHIM LTD. (IL) | 2021-12-16 | — | — | US | disclosed |
| CN-112911934-A | Use of cyclodextrins as agrochemical delivery systems | 阿达玛马克西姆有限公司 | 2021-06-04 | — | — | CN | disclosed |
| EP-3790386-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | Adama Makhteshim Ltd. (IL) | 2021-03-17 | — | — | EP | disclosed |
| US-20210022335-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | ADAMA MAKHTESHIM LTD. (IL) | 2021-01-28 | — | — | US | disclosed |
| WO-2019215645-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | ADAMA MAKHTESHIM LTD. (IL) | 2019-11-14 | — | — | WO | disclosed |
| CN-103145640-A | Biphenyl-thiazolo-carboxamides | BAYER CROPSCIENCE AG | 2013-06-12 | — | — | CN | disclosed |
| EP-1149289-B1 | WHOLE CELL SELECTION UTILIZING AZLACTONE-FUNCTIONAL SUPPORTS | 3M INNOVATIVE PROPERTIES CO (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20020150951-A1 | Whole cell selection utilizing azlactone-functional supports | 3M INNOVATIVE PROPERTIES COMPANY | 2002-10-17 | — | — | US | disclosed |
| US-6379952-B1 | INCORPORATING AN AZLACTONE MOIETY INTO BASE POLYMER SUPPORTS, DERIVATIZING WITH A BIOACTIVE SUBSTANCE FOR THE DESIRED TYPE OF WHOLE CELL, ALLOWING TO BIND, SEPARATING; FOR USE WITH BONE MARROW AND BLOOD MIXTURE FOR EXAMPLE | 3M INNOVATIVE PROPERTIES COMPANY | 2002-04-30 | — | — | US | disclosed |
| EP-1149289-A1 | WHOLE CELL SELECTION UTILIZING AZLACTONE-FUNCTIONAL SUPPORTS | 3M Innovative Properties Company (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0927143-B1 | GLASS ARTICLE HAVING SURFACE COATING AND METHOD FOR PRODUCING THE SAME | NIPPON ELECTRIC GLASS CO (JP) | 2001-10-17 | — | — | EP | disclosed |
| US-6280849-B1 | Glass article having surface coating of boric acid and method for producing the same | NIPPON ELECTRIC GLASS CO. LTD. (JP) | 2001-08-28 | — | — | US | disclosed |
| WO-2000045174-A1 | WHOLE CELL SELECTION UTILIZING AZLACTONE-FUNCTIONAL SUPPORTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-03 | — | — | WO | disclosed |
| US-5973104-A | CHAIN EXTENSION REACTION OF A LOW MOLECULAR POLYALKYLENE OXIDE OF 1,000 TO 30,000 IN NUMBER-AVERAGE MOLECULAR WEIGHT WITH A POLYVALENT ACID ANHYDRIDE, NEUTRALIZATION | NIPPON SHOKUBAI CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0927143-A1 | GLASS ARTICLE HAVING SURFACE COATING OF BORIC ACID AND METHOD FOR PRODUCING THE SAME | NIPPON ELECTRIC GLASS CO., LTD (JP) | 1999-07-07 | — | — | EP | disclosed |
| WO-1999003791-A1 | GLASS ARTICLE HAVING SURFACE COATING OF BORIC ACID AND METHOD FOR PRODUCING THE SAME | NIPPON ELECTRIC GLASS CO., LTD. (JP) | 1999-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210022335-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | GYS2, DDT, PTPRG | CA1 445/4885CA2 106/4885CA9 504/4885 |
| US-12127559-B2 | Use of cyclodextrins as agrochemical delivery system | DDT, GYS2, ACHE | CA1 686/4885CA2 66/4885CA9 466/4885 |
| US-20210386067-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | DDT, GYS2, ACHE | CA1 686/4885CA2 66/4885CA9 466/4885 |
| US-20250057161-A1 | USE OF CYCLODEXTRINS AS AGROCHEMICAL DELIVERY SYSTEM | DDT, GYS2, ACHE | CA1 686/4885CA2 66/4885CA9 466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.