SCHEMBL7149290

SCHEMBL7149290

NC(Cc1ccc(O)cc1)C(=O)NC(CS)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MME P08473 8/20 0.60
SLC7A5 Q01650 1/20 0.59
YARS1 P54577 2/20 0.56
ACE P12821 2/20 0.52
CPA1 P15085 1/20 0.52
ACE2 Q9BYF1 1/20 0.52
ENPEP Q07075 1/20 0.49
OPRD1 P41143 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7149294 1.00 MME (0.60) MMESLC7A5YARS1ACECPA1
SCHEMBL30326195 1.00 MME (0.60) MMESLC7A5YARS1ACECPA1
SCHEMBL30287990 0.96 MME (0.60) MMESLC7A5YARS1ACECPA1
SCHEMBL30287993 0.96 MME (0.60) MMESLC7A5YARS1ACECPA1
SCHEMBL31025679 0.96 MME (0.60) MMESLC7A5YARS1ACECPA1
Water SCHEMBL7150501 0.96 MME (0.56) MMESLC7A5YARS1ACECPA1
SCHEMBL30788342 0.94 MME (0.54) MMESLC7A5YARS1ACECPA1
SCHEMBL30288033 0.92 MME (0.66) MMEACEOPRD1
SCHEMBL30288011 0.92 MME (0.66) MMEACEOPRD1
SCHEMBL30288043 0.92 MME (0.66) MMEACEOPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024161169-A1 ACROSS BLOOD BRAIN BARRIER DELIVERY OF TOLL-LIKE RECEPTORS LIGANDS AND THERAPIES THEREOF BIOASIS TECHNOLOGIES, INC. (CA) 2024-08-08 WO claimed
EP-4157358-A1 COMPOSITIONS AND METHODS FOR TREATING FRONTOTEMPORAL DEMENTIA biOasis Technologies Inc. (CA) 2023-04-05 EP claimed
EP-4132563-A1 COMPOSITIONS AND METHODS FOR TREATING LEWY BODY DEMENTIA biOasis Technologies Inc. (CA) 2023-02-15 EP claimed
CN-105407907-A Uric acid level lowering agent SUNTORY HOLDINGS LTD 2016-03-16 CN claimed
EP-4634396-A1 BIOBASED SYNTHESIS OF GLUCODIAMINE Solugen, Inc. (US) 2025-10-22 EP disclosed
WO-2025076549-A1 SMALL MOLECULE ACTIVATORS SOLUGEN, INC. (US) 2025-04-10 WO disclosed
WO-2024161169-A1 ACROSS BLOOD BRAIN BARRIER DELIVERY OF TOLL-LIKE RECEPTORS LIGANDS AND THERAPIES THEREOF BIOASIS TECHNOLOGIES, INC. (CA) 2024-08-08 WO disclosed
WO-2024129887-A1 BIOBASED SYNTHESIS OF GLUCODIAMINE SOLUGEN, INC. (US) 2024-06-20 WO disclosed
US-20230399374-A1 Compounds, Compositions and Methods of Use to Treat Bone Fractures NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-12-14 US disclosed
CN-116801900-A Compounds, compositions and methods of use for treating bone fractures 普渡研究基金会 2023-09-22 CN disclosed
EP-4232074-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT BONE FRACTURES Purdue Research Foundation (US) 2023-08-30 EP disclosed
CN-110075315-B Antibody conjugate, and preparation method and application thereof 上海复旦张江生物医药股份有限公司 2023-08-11 CN disclosed
EP-0866684-A1 COSMETIC HAIR TREATMENT METHOD UNILEVER PLC (GB) 1998-09-30 EP disclosed
WO-1997022329-A1 COSMETIC HAIR TREATMENT METHOD UNILEVER PLC (GB) 1997-06-26 WO disclosed
EP-0457701-B1 Derivatives of endogenous mediators, their salts, process for preparation, application and compositions containing them IMMUNOTECH SA (FR) 1995-02-22 EP disclosed
US-5298491-A Derivatives of endogenous mediators, their salts, method of preparation, applications and compositions in which they are present IMMUNOTECH (FR) 1994-03-29 US disclosed
EP-0457701-A1 Derivatives of endogenous mediators, their salts, process for preparation, application and compositions containing them IMMUNOTECH S.A. (FR) 1991-11-21 EP disclosed
EP-0145386-B1 DERIVATIZED POLYSTYRENE AND OTHER POLYMER SUPPORTS FOR SPECTROSCOPIC STUDIES CITY OF HOPE NATIONAL MEDICAL CENTER (US) 1991-05-15 EP disclosed
US-4978724-A Method of preparing derivatized polystyrene for spectroscopic studies APPLIED IMMUNESCIENCES, INC. (US) 1990-12-18 US disclosed
EP-0145386-A2 Derivatized polystyrene and other polymer supports for spectroscopic studies CITY OF HOPE NATIONAL MEDICAL CENTER (US) 1985-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230399374-A1 Compounds, Compositions and Methods of Use to Treat Bone Fractures SOST, BMP2, BMP4 MME 630/4885SLC7A5 3739/4885YARS1 4872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.