SCHEMBL4337978

SCHEMBL4337978

[c]1nc2c(-c3ccccc3)cccc2s1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIMK1 P53667 3/20 0.39
ENPP1 P22413 2/20 0.35
F9 P00740 1/20 0.35
ALDH1A1 P00352 3/20 0.34
HSD17B10 Q99714 2/20 0.34
HPGD P15428 1/20 0.34
BCL2L1 Q07817 1/20 0.34
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34
KDR P35968 2/20 0.34
RET P07949 1/20 0.34
FLT1 P17948 1/20 0.34
MAPK14 Q16539 1/20 0.34
METAP2 P50579 1/20 0.33
TNF P01375 1/20 0.33
MAP4K4 O95819 1/20 0.33
CSF1R P07333 1/20 0.33
FGFR1 P11362 1/20 0.33
PDGFRA P16234 1/20 0.33
LTK P29376 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411212 0.88
SCHEMBL16150637 0.87 NOTUM (0.38) ALDH1A1TNFFGFR1ACVR1
SCHEMBL5535527 0.82 ABL1 (0.42) ENPP1ALDH1A1HSD17B10HPGDMAPK1
SCHEMBL7754182 0.79 KDM4E (0.37) ALDH1A1HSD17B10HPGDMAPK1TNF
SCHEMBL21351983 0.78
SCHEMBL9837227 0.78 KDM4E (0.41) ALDH1A1HSD17B10HPGDMAPK1TDO2
SCHEMBL2679046 0.76 KDM4E (0.40) ALDH1A1HSD17B10
SCHEMBL9050105 0.76 TGFBR1 (0.41) ALDH1A1MAPK14ACVR1
SCHEMBL11200488 0.75
SCHEMBL6487723 0.75 LIMK1 (0.30) LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO claimed
US-11873432-B2 Luminescent materials including a luminescent benzothiazole, articles including a security feature, and methods of forming luminescent particles including a luminescent benzothiazole HONEYWELL INTERNATIONAL INC. (US) 2024-01-16 US claimed
EP-3887477-B1 LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE HONEYWELL INT INC (US) 2024-01-03 EP claimed
US-20230043400-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2023-02-09 US claimed
EP-3887477-A1 LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE Honeywell International Inc. (US) 2021-10-06 EP claimed
CN-113330093-A Luminescent materials comprising luminescent benzothiazole, articles including security features, and methods of forming luminescent particles comprising luminescent benzothiazole 霍尼韦尔国际公司 2021-08-31 CN claimed
US-20200317691-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2020-10-08 US claimed
US-20200172803-A1 LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE HONEYWELL INTERNATIONAL INC. (US) 2020-06-04 US claimed
WO-2020113016-A1 LUMINESCENT MATERIALS INCLUDING A LUMINESCENT BENZOTHIAZOLE, ARTICLES INCLUDING A SECURITY FEATURE, AND METHODS OF FORMING LUMINESCENT PARTICLES INCLUDING A LUMINESCENT BENZOTHIAZOLE HONEYWELL INTERNATIONAL INC. (US) 2020-06-04 WO claimed
EP-3414239-A2 INHIBITORS OF RECEPTOR-INTERACTING PROTEIN KINASE 1 Denali Therapeutics Inc. (US) 2018-12-19 EP claimed
US-10131676-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2018-11-20 US claimed
US-20180099981-A1 COMPOUNDS, COMPOSITIONS AND METHODS DENALI THERAPEUTICS INC. 2018-04-12 US claimed
US-9815850-B2 Compounds, compositions and methods DENALI THERAPEUTICS INC. (US) 2017-11-14 US claimed
WO-2017136727-A2 COMPOUNDS, COMPOSITIONS AND METHODS DENALI THERAPEUTICS INC. (US) 2017-08-10 WO claimed
US-8852755-B2 Oxadiazole metallic complexes and their electronic and opto-electronic applications MERCK PATENT GMBH (DE) 2014-10-07 US claimed
US-4225682-A PEPTIZED DENKA CHEMICAL CORPORATION (US) 1980-09-30 US claimed
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO disclosed
US-20240150376-A1 Compounds, Compositions and Methods DENALI THERAPEUTICS INC. (US) 2024-05-09 US disclosed
US-3979369-A DIENE POLYMER MONSANTO COMPANY (US) 1976-09-07 US disclosed
US-3974170-A SULFONATES, SULFINATES MONSANTO COMPANY (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180099981-A1 COMPOUNDS, COMPOSITIONS AND METHODS PIK3CA, PLK1, PIK3CB LIMK1 554/4885ENPP1 900/4885F9 4574/4885
US-20200317691-A1 Compounds, Compositions and Methods PIK3CA, PLK1, PIK3CB LIMK1 554/4885ENPP1 900/4885F9 4574/4885
US-20240150376-A1 Compounds, Compositions and Methods PIK3CA, PLK1, PIK3CB LIMK1 554/4885ENPP1 900/4885F9 4574/4885
US-10131676-B2 Compounds, compositions and methods PIK3CA, PLK1, PIK3CB LIMK1 554/4885ENPP1 900/4885F9 4574/4885
US-20230043400-A1 Compounds, Compositions and Methods PIK3CA, PLK1, PIK3CB LIMK1 554/4885ENPP1 900/4885F9 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.