SCHEMBL7149451

SCHEMBL7149451

Cc1cc(F)c(F)c(F)c1S(N)(=O)=O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.59
CA2 P00918 13/20 0.59
CA12 O43570 10/20 0.59
CA7 P43166 10/20 0.59
CA13 Q8N1Q1 10/20 0.59
SOS1 Q07889 1/20 0.39
CA9 Q16790 2/20 0.38
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
CYP1A2 P05177 1/20 0.37
PTGS1 P23219 4/20 0.37
PTGS2 P35354 4/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10675603 0.79 CA1 (0.39) CA1CA2CA12CA7CA13
SCHEMBL13099828 0.77 CA1 (0.48) CA1CA2CA12CA7CA13
SCHEMBL7149455 0.75 CA2 (0.72) CA1CA2CA12CA7CA13
SCHEMBL2776018 0.75 CA2 (1.00) CA1CA2CA12CA7CA13
SCHEMBL21808336 0.74 CA12 (0.48) CA1CA2CA12CA7CA13
SCHEMBL113366 0.70 CA1 (0.52) CA1CA2CA12CA7CA13
SCHEMBL13282667 0.70 CA1 (0.70) CA1CA2CA12CA7CA13
SCHEMBL20150026 0.70 KDM4E (0.45) CA1CA2CA12CA7CA13
SCHEMBL26382471 0.69 CA12 (0.42) CA1CA2CA12CA7CA13
SCHEMBL571331 0.69 CA1 (1.00) CA1CA2CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1351570-A1 SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITION Sumitomo Chemical Takeda Agro Company, Limited (JP) 2003-10-15 EP disclosed
WO-2003075659-A1 SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITIONS SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2003-09-18 WO disclosed
WO-2002054867-A1 SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITION SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2002-07-18 WO disclosed