SCHEMBL2776018

SCHEMBL2776018

NS(=O)(=O)c1c(F)c(F)cc(F)c1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 1.00
CA1 P00915 19/20 1.00
CA12 O43570 12/20 1.00
CA7 P43166 12/20 1.00
CA13 Q8N1Q1 11/20 1.00
CA9 Q16790 7/20 0.47
CA4 P22748 3/20 0.43
CA6 P23280 2/20 0.43
CA5A P35218 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA5B Q9Y2D0 2/20 0.43
CA3 P07451 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7149455 0.84 CA2 (0.72) CA2CA1CA12CA7CA13
SCHEMBL7731560 0.78 CA2 (0.64) CA2CA1CA12CA7CA13
SCHEMBL571331 0.77 CA1 (1.00) CA2CA1CA12CA7CA13
SCHEMBL31000067 0.77 CA1 (0.62) CA2CA1CA12CA7CA13
SCHEMBL2776177 0.77 CA1 (0.62) CA2CA1CA12CA7CA13
SCHEMBL2000976 0.75 CA1 (0.59) CA2CA1CA12CA7CA13
SCHEMBL7149451 0.75 CA1 (0.59) CA2CA1CA12CA7CA13
SCHEMBL29216110 0.75 CA1 (0.94) CA2CA1CA12CA7CA13
SCHEMBL2779769 0.74 CA1 (0.56) CA2CA1CA12CA7CA13
SCHEMBL1497205 0.74 CA1 (0.59) CA2CA1CA12CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN claimed
US-20150266900-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2015-09-24 US claimed
CN-120005064-A Aryl ion polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2025-05-16 CN disclosed
CN-119219809-A Fluorine-containing polymer, preparation method thereof and ion exchange membrane 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
CN-119219810-A Ionic polymer and preparation method and application thereof 佛山绿动氢能科技有限公司 2024-12-31 CN disclosed
EP-3172264-B1 NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS TO THE METHODS FOR THE PRODUCTION THEREOF, AND TO THE USES OF SAME AS ELECTROLYTES FOR BATTERIES CDP INNOVATION (FR) 2021-06-16 EP disclosed
CN-107001622-B Novel polymers containing grafted sodium or lithium bis (sulfonyl) imide salts, method for the production thereof and use thereof as battery electrolytes CDP创新公司 2020-01-07 CN disclosed
US-10141603-B2 Polymers containing grafted bis(sulfonyl)imide sodium or lithium salts, methods for production thereof and uses of same as electrolytes for batteries CPD INNOVATION (FR) 2018-11-27 US disclosed
US-9725467-B2 Fluorinated benzenesulfonamides as inhibitors of carbonic anhydrase VILNIUS UNIVERSITY (LT) 2017-08-08 US disclosed
US-9725467-B2 Fluorinated benzenesulfonamides as inhibitors of carbonic anhydrase VILNIUS UNIVERSITY (LT) 2017-08-08 US disclosed
US-9725467-B2 Fluorinated benzenesulfonamides as inhibitors of carbonic anhydrase VILNIUS UNIVERSITY (LT) 2017-08-08 US disclosed
US-20150266900-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2015-09-24 US disclosed
US-20150266900-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2015-09-24 US disclosed
EP-2914583-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE Vilnius University (LT) 2015-09-09 EP disclosed
WO-2014062044-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE VILNIUS UNIVERSITY (LT) 2014-04-24 WO disclosed
EP-2147915-B1 New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them SERVIER LAB (FR) 2010-09-15 EP disclosed
US-7741320-B2 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2010-06-22 US disclosed
EP-2147915-A1 New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them Les Laboratoires Servier (FR) 2010-01-27 EP disclosed
WO-2010004139-A1 NEW CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM LES LABORATOIRES SERVIER (FR) 2010-01-14 WO disclosed
US-20100009974-A1 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them LES LABORATOIRES SERVIER (FR) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266900-A1 FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE CA9, CA7, CA2 CA2 3/4885CA1 7/4885CA12 9/4885
US-20100009974-A1 Cycloalkylated benzothiadiazines, a process for their preparation and pharmaceutical compostions containing them ACLY, HCAR1, GABRG1 CA2 1509/4885CA1 3557/4885CA12 4272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.