Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 18/20 | 0.72 |
| ▸ | CA1 | P00915 | 17/20 | 0.72 |
| ▸ | CA12 | O43570 | 8/20 | 0.72 |
| ▸ | CA7 | P43166 | 8/20 | 0.72 |
| ▸ | CA13 | Q8N1Q1 | 7/20 | 0.72 |
| ▸ | CA9 | Q16790 | 8/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776018 | 0.84 | CA2 (1.00) | CA2CA1CA12CA7CA13 | |
| SCHEMBL7149451 | 0.75 | CA1 (0.59) | CA2CA1CA12CA7CA13 | |
| SCHEMBL603929 | 0.71 | CA2 (0.55) | CA2CA1CA12CA7CA13 | |
| SCHEMBL1245850 | 0.71 | CA1 (0.43) | CA2CA1CA12CA7CA13 | |
| SCHEMBL13282667 | 0.70 | CA1 (0.70) | CA2CA1CA12CA7CA13 | |
| SCHEMBL4137374 | 0.70 | CA1 (0.41) | CA2CA1CA12CA7CA13 | |
| SCHEMBL7731560 | 0.69 | CA2 (0.64) | CA2CA1CA12CA7CA13 | |
| SCHEMBL2776177 | 0.69 | CA1 (0.62) | CA2CA1CA12CA7CA13 | |
| SCHEMBL31000067 | 0.69 | CA1 (0.62) | CA2CA1CA12CA7CA13 | |
| SCHEMBL24495369 | 0.67 | CA1 (0.71) | CA2CA1CA12CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725467-B2 | Fluorinated benzenesulfonamides as inhibitors of carbonic anhydrase | VILNIUS UNIVERSITY (LT) | 2017-08-08 | — | — | US | disclosed |
| US-20150266900-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | VILNIUS UNIVERSITY (LT) | 2015-09-24 | — | — | US | disclosed |
| EP-1351570-A1 | SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITION | Sumitomo Chemical Takeda Agro Company, Limited (JP) | 2003-10-15 | — | — | EP | disclosed |
| WO-2003075659-A1 | SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITIONS | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2003-09-18 | — | — | WO | disclosed |
| WO-2002054867-A1 | SULFONAMIDE DERIVATIVE-CONTAINING AGRICULTURAL AND HORTICULTURAL COMPOSITION | SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266900-A1 | FLUORINATED BENZENESULFONAMIDES AS INHIBITORS OF CARBONIC ANHYDRASE | CA9, CA7, CA2 | CA2 3/4885CA1 7/4885CA12 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.