Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.33 |
| ▸ | HTR1A | P08908 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151669 | 0.71 | EPHX2 (0.35) | CYP2D6MEN1LMNAHRH1SCN1A | |
| SCHEMBL3129709 | 0.67 | SLC6A2 (0.55) | HRH1SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL26414363 | 0.64 | CES2 (0.40) | CYP2D6MEN1LMNAHRH1SCN1A | |
| SCHEMBL1054006 | 0.63 | SLC6A2 (0.46) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1002940 | 0.63 | TACR1 (0.33) | CYP2D6HRH1SLC6A3HTR1AKCNH2 | |
| SCHEMBL24252041 | 0.62 | HTR2C (0.34) | KCNH2HCRTR1HCRTR2 | |
| SCHEMBL1060655 | 0.62 | SLC6A2 (0.47) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1060653 | 0.62 | SLC6A2 (0.47) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1059404 | 0.62 | SLC6A2 (0.47) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3899463 | 0.61 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1337529-A2 | HETEROCYCLYLALKYL PIPERIDINE DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002040474-A2 | HETEROCYCLYLALKYL PIPERIDINE DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2002-05-23 | — | — | WO | disclosed |