Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151464 | 0.76 | KCNN4 (0.35) | KCNN4TSHRALDH1A1MAPK1NR1H2 | |
| SCHEMBL7146065 | 0.73 | KCNN4 (0.37) | KCNN4TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL7142469 | 0.72 | ESR1 (0.31) | — | |
| SCHEMBL2454534 | 0.72 | KCNN4 (0.39) | KCNN4TSHRALDH1A1CYP1A2PTPN1 | |
| SCHEMBL7147541 | 0.68 | KCNN4 (0.39) | KCNN4TSHRALDH1A1MAPK1CYP2C19 | |
| SCHEMBL7151470 | 0.67 | KCNN4 (0.35) | KCNN4TSHRALDH1A1MAPK1NR1H2 | |
| SCHEMBL7145128 | 0.66 | KCNN4 (0.36) | KCNN4CYP1A2MAPK1NR1H2NR1H3 | |
| SCHEMBL3526796 | 0.64 | ESR1 (0.37) | KCNN4TSHRALDH1A1MAPTKMT2A | |
| SCHEMBL1049841 | 0.64 | ALDH1A1 (0.41) | TSHRALDH1A1PTPN1CA1CA2 | |
| SCHEMBL10827620 | 0.62 | KCNN4 (0.45) | KCNN4TSHRALDH1A1CYP1A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518375-B1 | Trivalent alkyl chromium compound catalyst for the production of an ethylene polymer | JAPAN POLYOLEFINS CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1041085-B1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | JAPAN POLYOLEFINS CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1041085-A1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | Japan Polyolefins Co., Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |