Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.54 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148309 | 0.85 | MAPT (0.68) | USP2MAPTCDK2MEN1KMT2A | |
| SCHEMBL7153529 | 0.84 | NPC1 (0.69) | USP2MAPTCDK2MEN1KMT2A | |
| SCHEMBL23013358 | 0.81 | USP2 (0.68) | USP2MAPTLMNAMEN1KMT2A | |
| SCHEMBL7154056 | 0.81 | ALDH1A1 (0.66) | USP2MAPTCDK2MEN1KMT2A | |
| SCHEMBL1675926 | 0.80 | USP2 (0.67) | USP2MAPTLMNAMEN1KMT2A | |
| SCHEMBL6788342 | 0.80 | ALDH1A1 (0.61) | USP2MAPTCDK2LMNAMEN1 | |
| SCHEMBL7151978 | 0.77 | CDK2 (0.61) | USP2MAPTCDK2LMNAMEN1 | |
| SCHEMBL5124270 | 0.77 | ALDH1A1 (0.66) | USP2MAPTLMNAMEN1KMT2A | |
| SCHEMBL392625 | 0.76 | ALDH1A1 (0.82) | MAPTLMNAMEN1KMT2AHPGD | |
| SCHEMBL7088328 | 0.76 | MAPT (0.68) | MAPTLMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |