Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148309 | 0.82 | MAPT (0.68) | CDK2KMT2AGAAMEN1F10 | |
| SCHEMBL7153529 | 0.81 | NPC1 (0.69) | CDK2KMT2AGAAMEN1F10 | |
| SCHEMBL7157515 | 0.80 | NPC1 (0.54) | CDK2KCNQ2KMT2AGAAPKM | |
| SCHEMBL7152061 | 0.80 | NPC1 (0.53) | CDK2KCNQ2KMT2AGAAPKM | |
| SCHEMBL7154056 | 0.78 | ALDH1A1 (0.66) | CDK2KMT2APKMMEN1ALDH1A1 | |
| SCHEMBL7149795 | 0.77 | USP2 (0.57) | CDK2KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6244643 | 0.75 | F10 (0.60) | KMT2AMEN1F10MAPTNPC1 | |
| SCHEMBL7150787 | 0.74 | RAB9A (0.54) | CDK2KCNQ2KMT2AGAAPKM | |
| SCHEMBL7157379 | 0.74 | NPY2R (0.60) | CDK2KCNQ2KMT2AGAAPKM | |
| SCHEMBL7153206 | 0.73 | RAB9A (0.53) | CDK2KCNQ2KMT2AGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | claimed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | claimed |