Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.38 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037132 | 0.94 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL9446147 | 0.81 | CYP3A4 (0.44) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL24946313 | 0.80 | CSNK2A2 (0.38) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL24806431 | 0.77 | CYP3A4 (0.52) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL23542357 | 0.77 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL142313 | 0.76 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL30048420 | 0.76 | ALDH1A1 (0.48) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL24945808 | 0.75 | ESR1 (0.39) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| Ammonia Solution, Strong SCHEMBL478297 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ALOX15HSD17B10TYRNR1I2 | |
| SCHEMBL30772983 | 0.74 | CA2 (0.52) | ALDH1A1ALOX15HSD17B10TYRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1133504-B1 | METHOD FOR PRODUCING MONOARYLOXY-ANSA-METALLOCENES | BASELL POLYOLEFINE GMBH (DE) | 2003-03-12 | — | — | EP | claimed |