Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7037132 | 0.86 | ALDH1A1 (0.45) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24806431 | 0.86 | CYP3A4 (0.52) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24945808 | 0.84 | ESR1 (0.39) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24945815 | 0.82 | DAO (0.35) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL30027143 | 0.81 | ALDH1A1 (0.48) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL70068 | 0.81 | ALDH1A1 (0.48) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL24946313 | 0.81 | CSNK2A2 (0.38) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL7149858 | 0.81 | ALDH1A1 (0.41) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL17375021 | 0.75 | TDP1 (0.47) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL3218264 | 0.75 | CYP3A4 (0.39) | CYP3A4MAPK1ALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235025-A | Cross-linkable thermotropic liquid crystalline aromatic polyester | HIMONT ITALIA S.R.L. (IT) | 1993-08-10 | — | — | US | claimed |
| EP-0383177-A2 | Cross-linkable thermotropic liquid crystalline aromatic polyesters | HIMONT ITALIA S.r.l. (IT) | 1990-08-22 | — | — | EP | claimed |
| US-5235025-A | Cross-linkable thermotropic liquid crystalline aromatic polyester | HIMONT ITALIA S.R.L. (IT) | 1993-08-10 | — | — | US | disclosed |
| EP-0383177-A2 | Cross-linkable thermotropic liquid crystalline aromatic polyesters | HIMONT ITALIA S.r.l. (IT) | 1990-08-22 | — | — | EP | disclosed |