SCHEMBL71501

SCHEMBL71501

COC(=O)c1cc(C(=O)OC)c(Cl)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
ABL1 P00519 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
LMNA P02545 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
MAPT P10636 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
HTT P42858 2/20 0.46
TSHR P16473 2/20 0.46
NQO2 P16083 1/20 0.46
ALDH1A1 P00352 1/20 0.46
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA7 P43166 2/20 0.45
CA9 Q16790 2/20 0.45
CA14 Q9ULX7 2/20 0.45
PDK2 Q15119 1/20 0.45
PDK4 Q16654 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19328690 0.93 GAA (0.55) GAAABL1MEN1KMT2ALMNA
SCHEMBL70011 0.93 GAA (0.58) GAAABL1MEN1KMT2ALMNA
SCHEMBL7762378 0.86 ABL1 (0.61) GAAABL1MEN1KMT2ALMNA
SCHEMBL30697733 0.86 GAA (0.67) GAAABL1MEN1KMT2ALMNA
SCHEMBL2849661 0.86 CFTR (0.45) GAAABL1MEN1KMT2ALMNA
SCHEMBL9248547 0.86 ALPL (0.50) GAAABL1MEN1KMT2ALMNA
SCHEMBL17118715 0.86 MAPT (0.47) GAAABL1MEN1KMT2ALMNA
SCHEMBL2879979 0.86 GAA (0.45) GAAABL1MEN1KMT2ALMNA
SCHEMBL31487952 0.86 MAPT (0.47) GAAABL1MEN1KMT2ALMNA
SCHEMBL1787222 0.86 GAA (0.67) GAAABL1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 GAA 1423/4885ABL1 2606/4885MEN1 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.