Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HRH2 | P25021 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035461 | 0.74 | MEN1 (0.71) | KMT2AMEN1 | |
| SCHEMBL7025618 | 0.74 | PDE3B (0.62) | PARP1KMT2AMEN1 | |
| SCHEMBL17549668 | 0.71 | KMT2A (0.84) | KMT2AHRH2HRH1DRD2SIGMAR1 | |
| SCHEMBL17444609 | 0.70 | PARP1 (0.64) | PARP1KMT2ASIGMAR1MEN1 | |
| SCHEMBL9759896 | 0.70 | CA12 (0.51) | PARP1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11042668 | 0.70 | HTR2A (0.58) | KMT2AHRH2HRH1DRD2SIGMAR1 | |
| SCHEMBL11745824 | 0.70 | KMT2A (0.54) | KMT2A | |
| SCHEMBL9824610 | 0.70 | KMT2A (0.61) | KMT2AHRH2HRH1DRD2HTR2A | |
| SCHEMBL18770805 | 0.69 | DRD2 (0.82) | KMT2ADRD2SIGMAR1HTR2AMEN1 | |
| SCHEMBL8527407 | 0.69 | NPC1 (0.44) | KMT2AHRH1DRD2HTR2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775697-B1 | Process for producing 1-substituted tetrahydroquinazolindionen | SUMITOMO CHEMICAL CO (JP) | 2003-02-12 | — | — | EP | disclosed |
| US-5994542-A | Process for producing 1-substituted tetrahydroquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-11-30 | — | — | US | disclosed |
| EP-0878468-A1 | Process for producing 1-substituted tetrahydroquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5756738-A | Process for producing 1-substituted tetrahydroquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0775697-A1 | Process for producing 1-substituted tetrahydroquinazolindionen | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-05-28 | — | — | EP | disclosed |