Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1827517 | 0.76 | PDE4B (0.46) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL7386723 | 0.76 | DRD2 (0.59) | NPC1RAB9ATSHRHTR1ADRD3 | |
| SCHEMBL4851937 | 0.74 | KDM4E (0.41) | NPC1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12658564 | 0.74 | MEN1 (0.41) | MEN1KMT2ALMNAKDM4EL3MBTL1 | |
| SCHEMBL28432024 | 0.74 | TSHR (0.72) | TSHRHTR1ADRD3CHRM2ADRA2A | |
| SCHEMBL7388601 | 0.74 | DRD2 (0.63) | ALDH1A1HTR1ADRD3ADRA1AKMT2A | |
| SCHEMBL7388115 | 0.73 | ALPL (0.48) | NPC1ALDH1A1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL11745824 | 0.73 | KMT2A (0.54) | NPC1ALDH1A1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL6763737 | 0.72 | MAPT (0.50) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8543066 | 0.72 | KDM4E (0.44) | NPC1ALDH1A1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784619-B1 | PHENYL-OXO-ALKYL-(4-PIPERIDINYL)BENZOATE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 1999-03-24 | — | — | EP | claimed |