Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 5/20 | 0.70 |
| ▸ | CASP3 | P42574 | 5/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 13/20 | 0.52 |
| ▸ | NPC1 | O15118 | 12/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6296021 | 0.95 | PLAU (0.63) | PLAUCASP3SENP7SENP8SENP6 | |
| SCHEMBL7336298 | 0.83 | PLAU (1.00) | PLAUCASP3SENP7SENP8SENP6 | |
| Trifluoroacetic Acid SCHEMBL6296020 | 0.81 | PLAU (0.45) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL8506821 | 0.75 | F10 (0.52) | PLAUF2PLGKLKB1PRSS1 | |
| SCHEMBL178984 | 0.73 | CASP3 (0.85) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL108116 | 0.71 | NPC1 (1.00) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL13561178 | 0.71 | NPC1 (0.76) | PLAUCASP3SENP7SENP8SENP6 | |
| SCHEMBL7128825 | 0.71 | PYGM (0.66) | CASP3SENP7SENP8SENP6RAB9A | |
| SCHEMBL4727186 | 0.70 | RAB9A (0.81) | CASP3SENP7SENP8SENP6RAB9A | |
| Trifluoroacetic Acid SCHEMBL6300672 | 0.70 | F10 (0.48) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |