SCHEMBL7150908

SCHEMBL7150908

CC(Cl)n1c2ccccc2c2cc(C=O)ccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.53
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
KIF11 P52732 2/20 0.41
KDM4E B2RXH2 4/20 0.40
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.40
PKM P14618 1/20 0.40
HTT P42858 1/20 0.40
NPY5R Q15761 1/20 0.39
SRC P12931 2/20 0.38
CYP2A6 P11509 1/20 0.37
PSEN1 P49768 2/20 0.37
PSEN2 P49810 2/20 0.37
APH1B Q8WW43 2/20 0.37
NCSTN Q92542 2/20 0.37
APH1A Q96BI3 2/20 0.37
PSENEN Q9NZ42 2/20 0.37
HPGD P15428 2/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4728764 0.88 MEN1 (0.56) PTGER4KMT2AMEN1KIF11KDM4E
SCHEMBL10799659 0.80 GPR3 (0.48) KMT2AMEN1KDM4EALDH1A1POLB
SCHEMBL29570020 0.79 PTGER4 (0.64) PTGER4KMT2AMEN1KDM4EALDH1A1
SCHEMBL718797 0.79 PTGER4 (0.64) PTGER4KMT2AMEN1KDM4EALDH1A1
SCHEMBL8687281 0.79 PTGER4 (0.49) PTGER4KMT2AMEN1KIF11KDM4E
SCHEMBL8651388 0.78 PTGER4 (0.63) PTGER4KMT2AMEN1KDM4EALDH1A1
SCHEMBL22166445 0.76 PTGER4 (0.56) PTGER4KMT2AMEN1KIF11KDM4E
SCHEMBL22166446 0.76 PTGER4 (0.56) PTGER4KIF11KDM4EALDH1A1POLB
SCHEMBL22166470 0.76 PTGER4 (0.56) PTGER4KMT2AMEN1KIF11KDM4E
SCHEMBL29507657 0.75 PTGER4 (0.70) PTGER4KMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 PTGER4 3447/4885KMT2A 2339/4885MEN1 3589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.