Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PRNP | P04156 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870482 | 0.85 | HSD17B10 (0.62) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL28473859 | 0.83 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL18301097 | 0.83 | ALDH1A1 (0.55) | L3MBTL1ATMALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13948871 | 0.83 | MAPT (0.54) | L3MBTL1ATMALDH1A1KDM4EHPGD | |
| SCHEMBL7422929 | 0.82 | GLA (0.56) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL28702281 | 0.81 | ALDH1A1 (0.63) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL4633858 | 0.81 | CYP1A2 (0.61) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL22636374 | 0.81 | ALDH1A1 (0.52) | L3MBTL1ATMALDH1A1KDM4EHSD17B10 | |
| SCHEMBL19403373 | 0.80 | MAPT (0.47) | L3MBTL1ATMALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28463128 | 0.80 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808003-A | Preparation method of thioether | 甘肃农业大学 | 2020-10-23 | — | — | CN | disclosed |
| WO-2016086015-A1 | MYOGLOBIN-BASED CATALYSTS FOR CARBENE TRANSFER REACTIONS | UNIVERSITY OF ROCHESTER (US) | 2016-06-02 | — | — | WO | disclosed |
| WO-2003057161-A2 | BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |