Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PRNP | P04156 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TYMS | P04818 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153877 | 0.85 | L3MBTL1 (0.60) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL28473859 | 0.82 | ALDH1A1 (0.55) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL18301097 | 0.82 | ALDH1A1 (0.55) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL8158427 | 0.81 | HSD17B10 (0.49) | HSD17B10ALDH1A1KDM4ENPC1MAPT | |
| SCHEMBL7422929 | 0.81 | GLA (0.56) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL22636374 | 0.80 | ALDH1A1 (0.52) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL4633858 | 0.80 | CYP1A2 (0.61) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL8045461 | 0.80 | HSD17B10 (0.47) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL28702281 | 0.80 | ALDH1A1 (0.63) | HSD17B10ALDH1A1KDM4ETP53HPGD | |
| SCHEMBL7379539 | 0.79 | PTGDR2 (0.50) | HSD17B10ALDH1A1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |