SCHEMBL7154167

SCHEMBL7154167

c1ccc(CN(Cc2ccccc2)c2ccc(-c3ccc(N(Cc4ccccc4)Cc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.69
TSHR P16473 4/20 0.59
NR1H2 P55055 3/20 0.55
NR1H3 Q13133 3/20 0.55
CNR2 P34972 4/20 0.53
TAAR1 Q96RJ0 3/20 0.50
CYP2D6 P10635 2/20 0.49
LMNA P02545 2/20 0.49
NR3C1 P04150 1/20 0.49
CYP1A2 P05177 1/20 0.49
HTR1A P08908 1/20 0.49
ADRA2A P08913 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
PDE6A P16499 1/20 0.49
ADRA2C P18825 1/20 0.49
MC4R P32245 1/20 0.49
ADRA1A P35348 1/20 0.49
HRH1 P35367 1/20 0.49
OPRM1 P35372 1/20 0.49
DRD3 P35462 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9320026 0.94 CYP2C19 (0.62) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL2960872 0.93 CYP2C19 (0.78) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL5369717 0.92 CYP2C19 (0.60) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL11334293 0.88 CYP2C19 (0.56) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL6496979 0.88 TAAR1 (0.61) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL12763733 0.88 CYP2C19 (0.85) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL43183 0.87 TSHR (0.74) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL17460822 0.87 TSHR (0.81) CYP2C19TSHRNR1H2NR1H3CNR2
SCHEMBL2011193 0.86 CYP2C19 (0.69) CYP2C19TSHRNR1H2NR1H3CNR2
Hydrochloric Acid SCHEMBL2139953 0.85 TSHR (0.71) CYP2C19TSHRNR1H2NR1H3CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US claimed
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US disclosed
US-5398105-A Method of electrophotographic wet reversal development MITSUBISHI PAPER MILLS LIMITED (JP) 1995-03-14 US disclosed
US-4520088-A COPOLYMER OF A STYRENE, AN ALKYL ACRYLATE WITH A C-4 OR GREATER ALKYL, AND A C-3 OR SMALLER ALKYL ACRYLATE MITSUBISHI PAPER MILLS, LTD. (JP) 1985-05-28 US disclosed
US-4500623-A Photoconductive compositions comprising an organic photoconductor and a thioamide compound and electrophotographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-19 US disclosed
US-4499167-A Photoconductive compositions comprising an organic photoconductor and an amide compound and electro-photographic light-sensitive materials using the compositions FUJI PHOTO FILM CO., LTD. (JP) 1985-02-12 US disclosed
US-4477547-A POLYAMIDE BINDER MITSUBISHI PAPER MILLS, LTD. (JP) 1984-10-16 US disclosed
US-4461818-A ETHCING WITH SOLUTION OF ALKALI AND/OR ALCOHOL MITSUBISHI PAPER MILLS LTD. (JP) 1984-07-24 US disclosed
US-4461821-A Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound FUJI PHOTO FILM CO., LTD. (JP) 1984-07-24 US disclosed
US-4448869-A HYDROXY AND CARBOXY OR ACYL SUBSTITUTED BENZENE OR NAPHTHALENE FUJI PHOTO FILM CO., LTD. (JP) 1984-05-15 US disclosed
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed