SCHEMBL5369717

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7154167	0.92	CYP2C19 (0.69)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL2011193	0.92	CYP2C19 (0.69)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL9320026	0.86	CYP2C19 (0.62)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL2960872	0.85	CYP2C19 (0.78)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL17460822	0.84	TSHR (0.81)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL15159187	0.82	CYP2C19 (0.89)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL43183	0.80	TSHR (0.74)	CYP2C19TSHRCNR2NR1H2NR1H3
	SCHEMBL23435088	0.80	NR3C2 (0.50)	CYP2C19TSHRCNR2TAAR1CYP2D6
	SCHEMBL21126417	0.80	TAAR1 (0.53)	CYP2C19TSHRCNR2TAAR1CYP2D6
	SCHEMBL25823394	0.80	NR3C2 (0.50)	CYP2C19TSHRCNR2TAAR1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.