Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DNM2 | P50570 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947117 | 0.87 | HCAR3 (0.56) | HCAR3L3MBTL1MAPK1NPC1GLA | |
| SCHEMBL8346115 | 0.83 | STK17A (0.48) | HCAR3L3MBTL1SMN1; SMN2PTK2ALDH1A1 | |
| SCHEMBL10736213 | 0.81 | STK17A (0.51) | L3MBTL1SMN1; SMN2PTK2ALDH1A1HPGD | |
| SCHEMBL12497548 | 0.80 | PTK2 (0.56) | HCAR3L3MBTL1MAPK1NPC1GLA | |
| SCHEMBL22265370 | 0.79 | HCAR3 (0.59) | HCAR3L3MBTL1CNR2ADRA2AADRA2B | |
| SCHEMBL7150739 | 0.79 | HCAR3 (0.59) | HCAR3MAPK1NPC1CNR2SMN1; SMN2 | |
| SCHEMBL26360961 | 0.78 | HCAR3 (0.57) | HCAR3L3MBTL1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11707466 | 0.78 | HCAR3 (0.57) | HCAR3CNR2SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL17604353 | 0.77 | MKNK1 (0.52) | L3MBTL1MAPK1NPC1GLATSHR | |
| SCHEMBL5206693 | 0.77 | MAOB (0.51) | L3MBTL1MAPK1NPC1TSHRADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632017-A | Synthetic method of 2-acetamido-5-chloropyridine | 山东友帮生化科技有限公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-0530524-B1 | Method of producing 2-amino-3-nitro-5-halogenopyridine | ICHIKAWA GOSEI KAGAKU KK (JP) | 2003-02-05 | — | — | EP | disclosed |
| US-5453512-A | Bromination of acylaminopyridine with 2-acylaminopyridinium hydorbromide | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |
| US-5290943-A | Halogenation of pyridine compound | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0530524-A1 | Method of producing 2-amino-3-nitro-5-halogenopyridine | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1993-03-10 | — | — | EP | disclosed |