Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 7/20 | 0.48 |
| ▸ | STK17B | O94768 | 4/20 | 0.48 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10736213 | 0.95 | STK17A (0.51) | STK17ASTK17BFERMT2F10ALDH1A1 | |
| SCHEMBL5206693 | 0.87 | MAOB (0.51) | STK17AFERMT2ALDH1A1HPGDKMT2A | |
| Hydrochloric Acid SCHEMBL6441856 | 0.86 | MAOB (0.50) | STK17AFERMT2ALDH1A1HPGDKMT2A | |
| SCHEMBL7154180 | 0.83 | HCAR3 (0.59) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17604353 | 0.77 | MKNK1 (0.52) | ALDH1A1HPGDKMT2ASMN1; SMN2MAOB | |
| SCHEMBL13947117 | 0.77 | HCAR3 (0.56) | ALDH1A1HPGDKMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8352280 | 0.76 | CHEK1 (0.48) | ALDH1A1HPGDHRH3 | |
| SCHEMBL8348152 | 0.76 | RAB9A (0.50) | F10ALDH1A1KMT2ASMN1; SMN2HRH3 | |
| SCHEMBL12477826 | 0.75 | CHEK1 (0.43) | — | |
| SCHEMBL11935676 | 0.74 | RAB9A (0.49) | F10ALDH1A1KMT2ASMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999021870-A1 | ERYTHROMYCIN A 11, 12-CARBAMATE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-06 | — | — | WO | disclosed |
| EP-0112707-B1 | AMINOPYRIMIDINONE DERIVATIVES AS HISTAMINE H1-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-11-04 | — | — | EP | disclosed |
| US-4652650-A | Pyridylaminoalkylamine intermediates | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-03-24 | — | — | US | disclosed |
| US-4548940-A | Pyridylaminoalkylaminopyrimidones useful as histamine H1 -antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-10-22 | — | — | US | disclosed |
| EP-0112707-A2 | Aminopyrimidinone derivatives as histamine H1-antagonists | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1984-07-04 | — | — | EP | disclosed |