SCHEMBL7154196

SCHEMBL7154196

Cc1ccccc1N(c1ccc(-c2ccc(N(c3ccccc3C)c3ccccc3C)cc2)cc1)c1ccccc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 3/20 0.36
LMNA P02545 3/20 0.36
SIGMAR1 Q99720 1/20 0.34
HSD17B1 P14061 3/20 0.34
HSD17B2 P37059 3/20 0.34
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13929896 1.00 ACHE (0.39) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL15306327 0.96 ALDH1A1 (0.38) ACHETSHRCYP3A4LMNAALDH1A1
SCHEMBL185396 0.94 CYP3A4 (0.43) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL1153906 0.94 CYP3A4 (0.43) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL13809090 0.94 TSHR (0.35) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL8943789 0.93 ACHE (0.45) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL19393440 0.91 ALDH1A1 (0.38) ACHETSHRCYP3A4LMNAALDH1A1
SCHEMBL73930 0.91 CYP3A4 (0.40) ACHETSHRCYP3A4LMNASIGMAR1
SCHEMBL17368989 0.91 ALDH1A1 (0.38) ACHETSHRCYP3A4LMNAALDH1A1
SCHEMBL13929897 0.91 CYP3A4 (0.40) ACHETSHRCYP3A4LMNASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US claimed
US-8354211-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge SHARP KABUSHIKI KAISHA (JP) 2013-01-15 US disclosed
US-8354211-B2 Electrophotographic photoreceptor, image forming apparatus and process cartridge SHARP KABUSHIKI KAISHA (JP) 2013-01-15 US disclosed
US-6532098-B1 Sandwiched between two electrically conductive substrates at least one of which is transparent; benzidine or phenylenediamine compounds, acryloyl-modified polyalkylene oxide; viologen compound NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-03-11 US disclosed