SCHEMBL1153906

SCHEMBL1153906

Cc1ccccc1N(c1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1)c1ccccc1C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.43
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
KDM4E B2RXH2 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
APP P05067 2/20 0.38
MEN1 O00255 1/20 0.37
CRHBP P24387 1/20 0.37
KMT2A Q03164 1/20 0.37
ATM Q13315 1/20 0.37
CRHR2 Q13324 1/20 0.37
TLR9 Q9NR96 1/20 0.37
TSHR P16473 1/20 0.35
ACHE P22303 1/20 0.35
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL185396 1.00 CYP3A4 (0.43) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL31390117 0.96 CYP3A4 (0.43) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL19102572 0.96 CYP3A4 (0.43) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL16324036 0.96 CYP3A4 (0.43) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL73930 0.94 CYP3A4 (0.40) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL15306327 0.94 ALDH1A1 (0.38) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL13929897 0.94 CYP3A4 (0.40) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL7154196 0.94 ACHE (0.39) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL13929896 0.94 ACHE (0.39) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2
SCHEMBL2887338 0.92 ALDH1A1 (0.39) CYP3A4ALDH1A1L3MBTL1KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7862967-B2 Photoconductors XEROX CORPORATION (US) 2011-01-04 US claimed
US-7771909-B2 Titanyl phthalocyanine photoconductors XEROX CORPORATION (US) 2010-08-10 US claimed
US-7718332-B2 Titanyl phthalocyanine silanol photoconductors XEROX CORPORATION (US) 2010-05-18 US claimed
US-7700250-B2 Titanyl phthalocyanine photoconductors XEROX CORPORATION (US) 2010-04-20 US claimed
US-7550239-B2 Alkyltriol titanyl phthalocyanine photoconductors XEROX CORPORATION (US) 2009-06-23 US claimed
US-20090004584-A1 HYDROXYGALLIUM PHTHALOCYANINE PROCESSES AND PHOTOCONDUCTORS THEREOF XEROX CORPORATION (US) 2009-01-01 US claimed
US-20090005555-A1 TITANYL PHTHALOCYANINE PROCESSES AND PHOTOCONDUCTORS THEREOF XEROX CORPORATION (US) 2009-01-01 US claimed
US-20080286669-A1 Photoconductors XEROX CORPORATION. 2008-11-20 US claimed
US-20080176155-A1 Alkyltriol titanyl phthalocyanine photoconductors XEROX CORPORATION 2008-07-24 US claimed
US-20080138726-A1 Titanyl phthalocyanine photoconductors XEROX CORPORATION 2008-06-12 US claimed
US-20080057422-A1 Titanyl phthalocyanine silanol photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20080057428-A1 Titanyl phthalocyanine photoconductors XEROX CORPORATION 2008-03-06 US claimed
US-20070298341-A1 Titanyl phthalocyanine photoconductors XEROX CORPORATION 2007-12-27 US claimed
US-7888502-B2 Titanyl phthalocyanine processes and photoconductors thereof XEROX CORPORATION (US) 2011-02-15 US disclosed
US-7862967-B2 Photoconductors XEROX CORPORATION (US) 2011-01-04 US disclosed
US-7771909-B2 Titanyl phthalocyanine photoconductors XEROX CORPORATION (US) 2010-08-10 US disclosed
US-20080057423-A1 Titanyl phthalocyanine silanol terphenyl photoconductors XEROX CORPORATION 2008-03-06 US disclosed
US-20070298341-A1 Titanyl phthalocyanine photoconductors XEROX CORPORATION 2007-12-27 US disclosed
US-20070298342-A1 Titanyl phthalocyanine photoconductors XEROX CORPORATION 2007-12-27 US disclosed
EP-0709747-B1 Selection of developing bias voltage for use in electrophotographic method using photosensitive material KYOCERA MITA CORP (JP) 2006-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090005555-A1 TITANYL PHTHALOCYANINE PROCESSES AND PHOTOCONDUCTORS THEREOF CRYAA, PRKCA, PRKCI CYP3A4 2459/4885ALDH1A1 701/4885L3MBTL1 3075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.