Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278879 | 0.78 | ALDH1A1 (0.46) | WDR5KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL7155154 | 0.75 | CYP19A1 (0.48) | WDR5KDM4EALDH1A1CYP19A1CYP1A2 | |
| SCHEMBL28808431 | 0.74 | ALDH1A1 (0.44) | ALDH1A1EDNRBEDNRAMAPT | |
| SCHEMBL28829408 | 0.74 | ALDH1A1 (0.44) | ALDH1A1EDNRBEDNRAGAA | |
| SCHEMBL880279 | 0.73 | TP53 (0.46) | KDM4EALDH1A1LMNAMAPK1CYP19A1 | |
| SCHEMBL12162742 | 0.73 | IDO1 (0.42) | WDR5KDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL12162752 | 0.72 | CYP19A1 (0.49) | KDM4EALDH1A1LMNAMAPK1CYP19A1 | |
| SCHEMBL7823623 | 0.71 | POLL (0.55) | KDM4EALDH1A1EDNRBEDNRAGAA | |
| SCHEMBL28850201 | 0.69 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP19A1EDNRBEDNRA | |
| SCHEMBL916737 | 0.69 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP19A1EDNRBEDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534627-B1 | Using FMOC (9-fluorenylmethyloxycarbonyl) and tert-butyl containing compounds as protecting group; efficiency and storage stability | RESEARCH CORPORATION TECNOLOGIES, INC. | 2003-03-18 | — | — | US | disclosed |