Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | FABP7 | O15540 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808431 | 0.80 | ALDH1A1 (0.44) | ALDH1A1EDNRBEDNRAMAPTHTR2A | |
| SCHEMBL28829408 | 0.76 | ALDH1A1 (0.44) | ALDH1A1EDNRBEDNRACA1CA2 | |
| SCHEMBL13938126 | 0.76 | ACHE (0.45) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27881140 | 0.72 | KDM4E (0.57) | ALDH1A1KDM4EHPGDCA1CA2 | |
| SCHEMBL6504577 | 0.71 | CYP1A2 (0.50) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL20478665 | 0.71 | PIN1 (0.52) | POLLKDM4ECA1CA2POLB | |
| SCHEMBL1847083 | 0.71 | PIN1 (0.52) | POLLKDM4ECA1CA2POLB | |
| SCHEMBL20480675 | 0.71 | PSMB5 (0.47) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| Nodulisporone SCHEMBL29991198 | 0.71 | POLL (1.00) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7154204 | 0.71 | WDR5 (0.45) | ALDH1A1KDM4EEDNRBEDNRAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |