Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 4/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | F3 | P13726 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7180418 | 0.93 | F2 (0.49) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6295012 | 0.89 | PLA2G7 (0.41) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6294978 | 0.89 | F2 (0.49) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.89 | F2 (0.48) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7158329 | 0.88 | PLA2G7 (0.42) | F2TMPRSS6PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7157101 | 0.88 | PLA2G7 (0.44) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7157714 | 0.88 | PLA2G7 (0.42) | F2TMPRSS6CCR2F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7158686 | 0.88 | F2 (0.45) | F2TMPRSS6PGRF10PRSS1 | |
| SCHEMBL6377229 | 0.88 | AKR1C3 (0.52) | F2TMPRSS6F10PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7154640 | 0.87 | PLA2G7 (0.46) | F2TMPRSS6F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |