Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7180418 | 0.95 | F2 (0.49) | AKR1C3F2KMT2AMEN1PRSS1 | |
| SCHEMBL6300754 | 0.89 | PRSS1 (0.47) | F2KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL6295817 | 0.88 | PLA2G7 (0.46) | F2KMT2AMEN1PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7154584 | 0.88 | F2 (0.44) | AKR1C3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8475188 | 0.86 | PRSS1 (0.44) | F2KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL6295821 | 0.86 | PLA2G7 (0.44) | F2KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL6300757 | 0.86 | PLA2G7 (0.44) | F2KMT2AMEN1PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL6294978 | 0.85 | F2 (0.49) | F2KMT2AMEN1PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.85 | F2 (0.48) | F2KMT2AMEN1PRSS1PRSS2 | |
| SCHEMBL6294700 | 0.85 | PRSS1 (0.55) | AKR1C3F2KMT2AMEN1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |