Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.49 |
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6377229 | 0.95 | AKR1C3 (0.52) | F2TMPRSS6AKR1C3MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7154584 | 0.93 | F2 (0.44) | F2TMPRSS6AKR1C3F3PRSS1 | |
| Trifluoroacetic Acid SCHEMBL6294978 | 0.90 | F2 (0.49) | F2TMPRSS6MEN1KMT2AF7 | |
| Trifluoroacetic Acid SCHEMBL7158713 | 0.90 | F2 (0.48) | F2TMPRSS6MEN1KMT2AF7 | |
| Trifluoroacetic Acid SCHEMBL7158686 | 0.89 | F2 (0.45) | F2TMPRSS6MEN1KMT2AF7 | |
| Trifluoroacetic Acid SCHEMBL7158329 | 0.89 | PLA2G7 (0.42) | F2TMPRSS6PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7157714 | 0.89 | PLA2G7 (0.42) | F2TMPRSS6PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7157101 | 0.89 | PLA2G7 (0.44) | F2TMPRSS6F7F3PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7154640 | 0.88 | PLA2G7 (0.46) | F2TMPRSS6MEN1KMT2AF7 | |
| Trifluoroacetic Acid SCHEMBL7154045 | 0.88 | PLA2G7 (0.43) | F2TMPRSS6MEN1KMT2AF7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312602-A1 | Amidino derivatives, and anticoagulants and thrombosis therapeutic agents containing them | Eisai Co., Ltd. (JP) | 2003-05-21 | — | — | EP | disclosed |