SCHEMBL7154659

SCHEMBL7154659

CC(C)=CCNC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24548358 0.81 MTNR1A (0.36)
SCHEMBL10050748 0.81 KDM4E (0.37)
SCHEMBL10417091 0.80 FNTA (0.65)
SCHEMBL10417090 0.80 FNTA (0.65)
SCHEMBL5315918 0.79 MTNR1A (0.35)
SCHEMBL10057719 0.79 TRPA1 (0.40)
SCHEMBL24548449 0.78 TDP1 (0.33)
SCHEMBL9650966 0.77
SCHEMBL1694511 0.77
SCHEMBL14542738 0.76 FNTA (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6555678-B1 Reacting with a silylating agent, extracting the silylated cellulose from the synthesis reaction medium, spinning through extrusion die(s), and treating the resultant yarn with a desilylation agent to regenerate the celluose and a siloxane RHODIA ACETOW (DE) 2003-04-29 US claimed
EP-1025291-B1 METHOD FOR PREPARING A REGENERATED CELLULOSE FIBRE OR YARN RHODIA ACETOW (DE) 2003-04-09 EP claimed
EP-4559918-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Genzyme Corporation (US) 2025-05-28 EP disclosed
EP-3673906-B1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORP (US) 2025-05-14 EP disclosed
CN-118344752-A Perovskite precursor solution for slot coating and application 北京大学深圳研究生院 2024-07-16 CN disclosed
CN-115710223-B Preparation method of 3-aryl quinolinone derivative 广东工业大学 2024-05-10 CN disclosed
CN-117820084-A Method for catalytic synthesis of 2, 5-dimethylphenol by using Lewis acid-cocatalyst system 西安元创化工科技股份有限公司 2024-04-05 CN disclosed
CN-115915882-A Multispectral detector and preparation method thereof 华中科技大学 2023-04-04 CN disclosed
CN-114605306-B Method for synthesizing organic sulfur compound based on alkyl xanthate and application thereof 南京师范大学 2022-07-29 CN disclosed
CN-114605306-A Method for synthesizing organic sulfur compound based on alkyl xanthate and application thereof 南京师范大学 2022-06-10 CN disclosed
CN-111587462-B Insulated wire 埃赛克斯古河电磁线日本有限公司 2022-04-08 CN disclosed
US-20160207933-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION 2016-07-21 US disclosed
US-9139580-B2 Glucosylceramide synthase inhibitors GENZYME CORPORATION (US) 2015-09-22 US disclosed
US-9126993-B2 Glucosylceramide synthase inhibitors GENZYME CORPORATION (US) 2015-09-08 US disclosed
US-20140371460-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION 2014-12-18 US disclosed
US-20140255381-A1 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION (US) 2014-09-11 US disclosed
EP-2685986-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS Genzyme Corporation (US) 2014-01-22 EP disclosed
WO-2012129084-A2 GLUCOSYLCERAMIDE SYNTHASE INHIBITORS GENZYME CORPORATION (US) 2012-09-27 WO disclosed
US-6555678-B1 Reacting with a silylating agent, extracting the silylated cellulose from the synthesis reaction medium, spinning through extrusion die(s), and treating the resultant yarn with a desilylation agent to regenerate the celluose and a siloxane RHODIA ACETOW (DE) 2003-04-29 US disclosed
CN-1122331-A Benzene, pyridine and pyrimidine derivative EISAI CO LTD (JP) 1996-05-15 CN disclosed