SCHEMBL7154758

SCHEMBL7154758

F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F.F[B-](F)(F)F.Ic1ccccc1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
MAPK1 P28482 1/20 0.42
BCAT2 O15382 1/20 0.40
PARP1 P09874 1/20 0.39
BACE1 P56817 1/20 0.39
DPP4 P27487 1/20 0.38
HTT P42858 1/20 0.38
HNF4A P41235 1/20 0.38
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30451343 0.92 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL154146 0.92 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Phosphine SCHEMBL28589614 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL28848116 0.88 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL6830189 0.87 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Naphthalene SCHEMBL27789647 0.85 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Iodobenzene SCHEMBL10487194 0.85 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Formaldehyde SCHEMBL29276839 0.85 PARP1 (0.43) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL27676479 0.85 CYP1A2 (0.48) ALDH1A1HSD17B10CYP2A6TDP1CASP3
SCHEMBL15484734 0.84 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635406-B1 Method of producing vertical interconnects between thin film microelectronic devices and products comprising such vertical interconnects KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2003-10-21 US disclosed
EP-1145339-A1 METHOD OF PRODUCING VERTICAL INTERCONNECTS BETWEEN THIN FILM MICROELECTRONIC DEVICES AND PRODUCTS COMPRISING SUCH VERTICAL INTERCONNECTS Koninklijke Philips Electronics N.V. (NL) 2001-10-17 EP disclosed
WO-2001033649-A1 METHOD OF PRODUCING VERTICAL INTERCONNECTS BETWEEN THIN FILM MICROELECTRONIC DEVICES AND PRODUCTS COMPRISING SUCH VERTICAL INTERCONNECTS KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 2001-05-10 WO disclosed