SCHEMBL154146

SCHEMBL154146

Ic1ccccc1-c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CYP2A6 P11509 1/20 0.48
MAPK1 P28482 1/20 0.48
BACE1 P56817 1/20 0.43
PARP1 P09874 1/20 0.43
DPP4 P27487 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
TDP1 Q9NUW8 1/20 0.39
BCAT2 O15382 1/20 0.39
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
TDO2 P48775 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30451343 1.00 ALDH1A1 (0.48) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Phosphine SCHEMBL28589614 0.97 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL6830189 0.95 ALDH1A1 (0.47) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL7154758 0.92 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Iodobenzene SCHEMBL10487194 0.92 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Formaldehyde SCHEMBL29276839 0.92 PARP1 (0.43) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Naphthalene SCHEMBL27789647 0.92 ALDH1A1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL15484734 0.92 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL28848116 0.90 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Boric Acid SCHEMBL29225672 0.90 ALDH1A1 (0.46) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119930614-A Benzo [4,5] imidazo [2,1-a ] isoquinoline compound and preparation method and application thereof 烟台大学 2025-05-06 CN claimed
CN-119504330-A One-step synthesis method of phenanthrene ring aromatic hydrocarbon derivative 常州大学 2025-02-25 CN claimed
CN-118637971-A Synthesis method of 2-methyl-4-phenylindene 上海毕臣生化科技有限公司 2024-09-13 CN claimed
CN-116836107-B Carbazol eight-membered ring large conjugated structure OLED material and preparation method thereof 西安欧得光电材料有限公司 2024-02-27 CN claimed
CN-116836107-A Carbazol eight-membered ring large conjugated structure OLED material and preparation method thereof 西安欧得光电材料有限公司 2023-10-03 CN claimed
CN-115745805-A Synthetic method of phenanthrene and naphthocycloheptene compounds 南通大学 2023-03-07 CN claimed
CN-110683926-B Preparation method of carboxylic acid aryl ester compound 北京大学深圳研究生院 2022-11-04 CN claimed
CN-113717018-A Preparation method of 9-benzylmethylfluorene compound 温州大学 2021-11-30 CN claimed
US-20210353631-A1 1,4-Benzoxazines for the Treatment of Cancers and Other Neurodegenerative Diseases Neugeneron LLC 2021-11-18 US claimed
CN-108530241-B Preparation method of benzo ring derivative with benzyl quaternary carbon center 武汉大学 2021-02-02 CN claimed
EP-0377634-B1 PROCESS FOR THE PREPARATION OF ARYL SULFIDES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-02 EP claimed
EP-0307446-B1 LIQUID PHASE ISOMERIZATION OF IODOAROMATIC COMPOUNDS EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-06-03 EP claimed
EP-0377634-A1 PROCESS FOR THE PREPARATION OF ARYL SULFIDES. EASTMAN KODAK CO (US) 1990-07-18 EP claimed
EP-0307458-A1 PROCESSES FOR ISOMERIZING AND OXIDATIVE IODINATING AROMATIC COMPOUNDS. EASTMAN KODAK CO (US) 1989-03-22 EP claimed
WO-1989001463-A1 PROCESS FOR THE PREPARATION OF ARYL SULFIDES EASTMAN KODAK COMPANY (US) 1989-02-23 WO claimed
US-4806698-A Liquid phase isomerization of iodoaromatic compounds EASTMAN KODAK COMPANY (US) 1989-02-21 US claimed
US-4806697-A NON-ACIDIC ZEOLITE CATALYSTS EASTMAN KODAK COMPANY (US) 1989-02-21 US claimed
US-4792641-A Process for preparing iodinated aromatic compounds EASTMAN KODAK COMPANY (US) 1988-12-20 US claimed
US-4792634-A HEATING IODOAROMATIC COMPOUND WITH SULFUR EASTMAN KODAK COMPANY (US) 1988-12-20 US claimed
WO-1988007511-A1 PROCESSES FOR ISOMERIZING AND OXIDATIVE IODINATING AROMATIC COMPOUNDS EASTMAN KODAK COMPANY (US) 1988-10-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210353631-A1 1,4-Benzoxazines for the Treatment of Cancers and Other Neurodegenerative Diseases GBA1, NFXL1, CYP4X1 ALDH1A1 123/4885HSD17B10 879/4885HPGD 320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.