SCHEMBL6830189

SCHEMBL6830189

Ic1ccccc1-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
HSD17B10 Q99714 3/20 0.44
BCL2L1 Q07817 2/20 0.44
MAPK1 P28482 2/20 0.44
HPGD P15428 1/20 0.44
CYP2A6 P11509 1/20 0.44
TAAR1 Q96RJ0 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MMP3 P08254 1/20 0.42
BACE1 P56817 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
PTGS2 P35354 1/20 0.40
PARP1 P09874 1/20 0.40
MEN1 O00255 1/20 0.40
APAF1 O14727 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30451343 0.95 ALDH1A1 (0.48) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL154146 0.95 ALDH1A1 (0.48) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL15484734 0.92 ALDH1A1 (0.46) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Phosphine SCHEMBL28589614 0.92 ALDH1A1 (0.46) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Biphenyl SCHEMBL10827614 0.89 HPRT1 (0.46) ALDH1A1MAPK1HPGDTDP1PTGS2
Biphenyl SCHEMBL10826986 0.89 CYP1A2 (0.62) ALDH1A1CYP2A6CYP1A2PTGS2NPC1
Formaldehyde SCHEMBL29276839 0.87 PARP1 (0.43) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
SCHEMBL7154758 0.87 ALDH1A1 (0.42) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Iodobenzene SCHEMBL10487194 0.87 ALDH1A1 (0.42) ALDH1A1HSD17B10BCL2L1MAPK1HPGD
Naphthalene SCHEMBL27789647 0.87 ALDH1A1 (0.42) ALDH1A1HSD17B10BCL2L1MAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101370769-B P-terphenyl compound mixture and electrophotographic photoreceptor prepared therefrom HODOGAYA CHEMICAL CO LTD 2015-04-01 CN claimed
CN-101370769-A P-terphenyl compound mixture and electrophotographic photoreceptor prepared therefrom HODOGAYA CHEMICAL CO LTD (JP) 2009-02-18 CN claimed
WO-2023239092-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
WO-2023239091-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-12-14 WO disclosed
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO LTD (KR) 2023-10-12 US disclosed
WO-2023146343-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-08-03 WO disclosed
WO-2022177374-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2022-08-25 WO disclosed
US-20220069240-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-03 US disclosed
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-07-11 US disclosed
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
CN-1753860-A Process for producing aromatic diamine derivative IDEMITSU KOSAN CO (JP) 2006-03-29 CN disclosed
EP-1226108-A4 DIARYL-ENYNES NPS ALLELIX CORP (CA) 2004-06-16 EP disclosed
US-6579987-B2 Reducing an ester containing ene-yne conjugated, silane and aryl or heteroaryl functionality to an alcohol; bromination, amination, desilanation, coupling and deprotecting NPS ALLELIX CORPORATION (CA) 2003-06-17 US disclosed
US-20030092769-A1 DIARYL-ENYNES NPS ALLELIX CORPORATION (CA) 2003-05-15 US disclosed
US-6525085-B2 Treating neurological and neuropsychiatric disorders NPS ALLELIX CORP. (CA) 2003-02-25 US disclosed
US-20020169197-A1 Diaryl-enynes NPS ALLELIX CORP. 2002-11-14 US disclosed
EP-1226108-A1 DIARYL-ENYNES NPS Allelix Corp. (CA) 2002-07-31 EP disclosed
US-6426364-B1 NERVOUS SYSTEM OR PSYCHOLOGICAL DISORDERS NPS ALLELIX CORP. (CA) 2002-07-30 US disclosed
WO-2001032602-A1 DIARYL-ENYNES NPS ALLELIX CORP. (CA) 2001-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214573-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALDH1A1 191/4885HSD17B10 1380/4885BCL2L1 4112/4885
US-20230329097-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OR10J3, OCIAD2, OCIAD1 ALDH1A1 191/4885HSD17B10 1380/4885BCL2L1 4112/4885
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device OR10J3, OR51E2, OXER1 ALDH1A1 154/4885HSD17B10 993/4885BCL2L1 4011/4885
US-20220069240-A1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME ORC3, LAGE3, ERCC1 ALDH1A1 1208/4885HSD17B10 3461/4885BCL2L1 2496/4885
US-20020169197-A1 Diaryl-enynes CBR3, CNR1, NR3C2 ALDH1A1 2117/4885HSD17B10 438/4885BCL2L1 749/4885
US-20030092769-A1 DIARYL-ENYNES CBR3, CNR1, CBR1 ALDH1A1 2120/4885HSD17B10 442/4885BCL2L1 738/4885
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 ALDH1A1 158/4885HSD17B10 987/4885BCL2L1 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.