SCHEMBL4740949

SCHEMBL4740949

O=C(Nc1ccccc1)c1cc(O)cc(O)c1

nearest known ligand 0.75

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 2/20 0.75
PTPN1 P18031 3/20 0.60
KCNK3 O14649 1/20 0.60
KCNK9 Q9NPC2 1/20 0.60
SIRT1 Q96EB6 2/20 0.58
HDAC2 Q92769 2/20 0.58
HDAC8 Q9BY41 2/20 0.58
HDAC6 Q9UBN7 2/20 0.58
KDM4E B2RXH2 1/20 0.58
POLB P06746 1/20 0.58
HDAC1 Q13547 1/20 0.58
DEGS1 O15121 2/20 0.57
ALOX5 P09917 1/20 0.57
HTT P42858 1/20 0.56
TOP1 P11387 2/20 0.55
TOP2A P11388 2/20 0.55
TOP2B Q02880 2/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17527523 0.88 NQO2 (0.59) NQO2PTPN1KCNK3KCNK9SIRT1
SCHEMBL2911616 0.87 HDAC2 (0.71) PTPN1KCNK3KCNK9SIRT1HDAC2
SCHEMBL715515 0.86 NQO2 (1.00) NQO2KDM4EPOLBDEGS1TOP1
SCHEMBL18648481 0.85 NQO2 (0.56) NQO2PTPN1KCNK3KCNK9SIRT1
SCHEMBL3863282 0.85 KMT2A (0.77) NQO2KCNK3KCNK9KDM4EPOLB
SCHEMBL2063559 0.85 KMT2A (0.77) KCNK3KCNK9SIRT1HDAC2HDAC8
SCHEMBL11154646 0.85 NQO2 (0.76) NQO2KDM4EPOLBDEGS1TOP1
SCHEMBL18063650 0.84 NQO2 (0.81) NQO2PTPN1KDM4EPOLBHDAC1
SCHEMBL1486873 0.84 NQO2 (0.75) NQO2PTPN1KCNK3KCNK9SIRT1
SCHEMBL17826843 0.84 NQO2 (0.54) NQO2PTPN1KCNK3KCNK9SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof SICHUAN UNIVERSITY (CN) 2026-02-24 US disclosed
US-20230235116-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT ANTI-DRIPPING COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF SICHUAN UNIVERSITY (CN) 2023-07-27 US disclosed
EP-4169967-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Sichuan University (CN) 2023-04-26 EP disclosed
CN-113817152-B Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2022-11-11 CN disclosed
CN-113817150-B Copolyester containing aromatic secondary amine structure and preparation method and application thereof 四川大学 2022-06-21 CN disclosed
WO-2021254391-A1 HIGH-TEMPERATURE SELF-CROSSLINKING-BASED FLAME-RETARDANT DROPLET-RESISTANT COPOLYESTER, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 四川大学 2021-12-23 WO disclosed
CN-113817150-A Copolyester containing aromatic secondary amine structure and preparation method and application thereof 四川大学 2021-12-21 CN disclosed
CN-113817152-A Flame-retardant anti-dripping copolyester based on high-temperature self-crosslinking and preparation method and application thereof 四川大学 2021-12-21 CN disclosed
US-20170216272-A1 COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-08-03 US disclosed
EP-3031461-A1 COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS The President and Fellows of Harvard College (US) 2016-06-15 EP disclosed
US-8017634-B2 Compositions for treating obesity and insulin resistance disorders PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2011-09-13 US disclosed
US-7544497-B2 Compositions for manipulating the lifespan and stress response of cells and organisms PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2009-06-09 US disclosed
US-20080280989-A1 Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same AMOREPACIFIC CORPORATION (KR) 2008-11-13 US disclosed
WO-2008089439-A2 METHODS AND COMPOSITIONS FOR ENHANCING LIFESPAN INVOLVING SIRTUIN-MODULATING COMPOUNDS AND CHALCOGENIDES FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2008-07-24 WO disclosed
EP-1765316-A2 METHODS AND COMPOSITIONS FOR MODULATING BAX-KU70-MEDIATED APOPTOSIS The President and Fellows of Harvard College (US) 2007-03-28 EP disclosed
US-20060084085-A1 Methods and compositions for modulating Bax-mediated apoptosis PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2006-04-20 US disclosed
US-20060084135-A1 Compositions for manipulating the lifespan and stress response of cells and organisms BIOMOL INTERNATIONAL, INC. 2006-04-20 US disclosed
WO-2006007411-A2 METHODS AND COMPOSITIONS FOR MODULATING BAX-MEDIATED APOPTOSIS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-01-19 WO disclosed
EP-0423163-A1 OXIDATIVE HAIR DYES Henkel Kommanditgesellschaft auf Aktien (DE) 1991-04-24 EP disclosed
WO-1990000047-A1 OXIDATIVE HAIR DYES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-01-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559589-B2 High-temperature self-crosslinking-based flame-retardant anti-dripping copolyester, and preparation method therefor and application thereof COL1A1, F11, COL2A1 NQO2 3772/4885PTPN1 3634/4885KCNK3 3463/4885
US-20080280989-A1 Hydroxybenzamide Derivatives, the Method For Preparing Thereof and the Cosmetic Composition Containing the Same H1-0, HAAO, H1-10 NQO2 413/4885PTPN1 4395/4885KCNK3 2712/4885
US-20170216272-A1 COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS FABP4, GPR119, SIRT1 NQO2 1759/4885PTPN1 2444/4885KCNK3 2703/4885
US-20060084085-A1 Methods and compositions for modulating Bax-mediated apoptosis BAX, BCL2, CASP3 NQO2 3645/4885PTPN1 3066/4885KCNK3 4254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.