SCHEMBL899585

SCHEMBL899585

O=C(Nc1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DEGS1 O15121 3/20 0.75
SNCA P37840 1/20 0.75
NQO2 P16083 2/20 0.73
POLB P06746 2/20 0.67
KDM4E B2RXH2 2/20 0.67
NPC1 O15118 4/20 0.65
RAB9A P51151 4/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
LMNA P02545 1/20 0.65
PKM P14618 1/20 0.65
APEX1 P27695 1/20 0.65
TDP1 Q9NUW8 1/20 0.65
TOP1 P11387 1/20 0.61
TP53 P04637 2/20 0.59
GAA P10253 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
PTPN1 P18031 1/20 0.59
ALOX15 P16050 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900928 1.00 DEGS1 (0.75) DEGS1SNCANQO2POLBKDM4E
SCHEMBL8420639 1.00 DEGS1 (0.75) DEGS1SNCANQO2POLBKDM4E
SCHEMBL20284045 0.94 DEGS1 (0.86) DEGS1SNCANQO2POLBKDM4E
SCHEMBL8770541 0.94 DEGS1 (0.68) DEGS1SNCANQO2POLBKDM4E
SCHEMBL11688443 0.92 DEGS1 (0.83) DEGS1SNCANQO2POLBKDM4E
SCHEMBL4491689 0.90 PTPN1 (0.76) DEGS1SNCANQO2POLBNPC1
SCHEMBL11676225 0.90 MEN1 (0.77) DEGS1SNCANQO2POLBKDM4E
SCHEMBL6555948 0.90 RAB9A (0.85) DEGS1SNCANQO2POLBKDM4E
SCHEMBL10439291 0.90 TRPV1 (0.67) DEGS1SNCANQO2POLBKDM4E
SCHEMBL2461226 0.90 MAPT (0.71) DEGS1SNCANQO2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119019910-B Water-based flame-retardant coating liquid for wood and preparation method thereof 江苏宜境科技有限公司 2025-02-14 CN claimed
CN-119019910-A Water-based flame-retardant coating liquid for wood and preparation method thereof 江苏宜境科技有限公司 2024-11-26 CN claimed
CN-114891199-A Preparation method of poly (fluorophenyl ester) polymer with high dielectric constant 西安交通大学 2022-08-12 CN claimed
US-20160031797-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF GTX, INC. 2016-02-04 US claimed
EP-0379057-B1 Mesogenic epoxy compounds DOW CHEMICAL CO (US) 2000-12-06 EP claimed
EP-0573573-B1 MESOGENIC GLYCIDYL AMINES DOW CHEMICAL CO (US) 1999-09-29 EP claimed
EP-0409069-B1 Mesogenic polycyanates and polycyanamides and thermosets thereof DOW CHEMICAL CO (US) 1999-06-02 EP claimed
US-5736620-A ENHANCED UNIDIRECTIONAL, MECHANICAL PROPERTIES AT LOWER TEMPERATURE THE DOW CHEMICAL COMPANY (US) 1998-04-07 US claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US claimed
EP-0670855-A1 NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS THE DOW CHEMICAL COMPANY (US) 1995-09-13 EP claimed
US-5248740-A Thioepoxides, liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1993-09-28 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5227452-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-07-13 US claimed
US-5218062-A Curable mixtures of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1993-06-08 US claimed
US-5182340-A Molding materials having shorter gel time with aliphatic amine curing agents THE DOW CHEMICAL COMPANY (US) 1993-01-26 US claimed
WO-1992015630-A2 MESOGENIC GLYCIDYL AMINES THE DOW CHEMICAL COMPANY (US) 1992-09-17 WO claimed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP claimed
EP-0473935-A2 Curable mixture of mesogenic epoxy resins and mesogenic polyamines and cured compositions THE DOW CHEMICAL COMPANY (US) 1992-03-11 EP claimed
EP-0409069-A2 Mesogenic polycyanates and thermosets thereof THE DOW CHEMICAL COMPANY (US) 1991-01-23 EP claimed
EP-0379057-A2 Mesogenic epoxy compounds THE DOW CHEMICAL COMPANY (US) 1990-07-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160031797-A1 ESTROGEN RECEPTOR LIGANDS AND METHODS OF USE THEREOF ESRRB, ESRRA, ESR2 DEGS1 4492/4885SNCA 4398/4885NQO2 2257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.