Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | CFD | P00746 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10334083 | 0.87 | CFD (0.63) | KDM4EHSD17B10ALDH1A1HPGDTDP1 | |
| SCHEMBL7411536 | 0.86 | TDP1 (0.69) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1162352 | 0.85 | TDP1 (0.56) | KDM4EALDH1A1HPGDCYP2C19TDP1 | |
| SCHEMBL2350573 | 0.85 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL2351442 | 0.84 | KDM4E (0.54) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL7199385 | 0.83 | HSD17B10 (0.56) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL25063116 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL24072456 | 0.83 | KDM4E (0.52) | KDM4EHSD17B10ALDH1A1HPGDCYP2C19 | |
| SCHEMBL28493212 | 0.81 | RORC (0.62) | KDM4EALDH1A1TDP1SMN1; SMN2MYC | |
| SCHEMBL7371976 | 0.81 | TDP1 (0.76) | KDM4EHSD17B10ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985927-A | Medicaments for the selective treatment of tumor tissues | KREUTZ WERNER (DE) | 1999-11-16 | — | — | US | claimed |
| EP-0817623-B1 | MEDICAMENTS FOR THE SELECTIVE TREATMENT OF TUMOUR TISSUES | KREUTZ WERNER PROF DR (DE) | 2003-11-12 | — | — | EP | disclosed |
| US-5985927-A | Medicaments for the selective treatment of tumor tissues | KREUTZ WERNER (DE) | 1999-11-16 | — | — | US | disclosed |
| US-4933330-A | PSORIASIS | DAK-LABORATORIET (DK) | 1990-06-12 | — | — | US | disclosed |
| EP-0291159-A2 | Aminosalicylic-acid derivatives for the treatment of psoriasis | DAK-LABORATORIET A/S (DK) | 1988-11-17 | — | — | EP | disclosed |
| US-4267174-A | AND PROCESS FOR ADMINISTERING | BOEHRINGER MANNHEIM, GMBH (DE) | 1981-05-12 | — | — | US | disclosed |
| US-4006239-A | Benzoic acid amides for mycobacterium infections | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |