Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464130 | 0.84 | FDPS (0.50) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL8649807 | 0.81 | FDPS (0.47) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL8656700 | 0.79 | FDPS (0.48) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL3691691 | 0.79 | FDPS (0.48) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL8088086 | 0.79 | FDPS (0.48) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL27589863 | 0.79 | FDPS (0.49) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL11904868 | 0.79 | FDPS (0.49) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL5017550 | 0.79 | FDPS (0.50) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL6950642 | 0.77 | ADORA2A (0.53) | FDPSLTA4HHDAC1HDAC6ADORA2A | |
| SCHEMBL5017009 | 0.77 | FDPS (0.49) | FDPSLTA4HHDAC1HDAC6ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | LEUKOMED, INC. | 2003-01-30 | — | — | US | disclosed |
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | LEUKOMED, INC. | 2003-01-30 | — | — | US | disclosed |
| WO-2002085916-A1 | 9-[(5-DIHYDROXYBORYL)-PENTYL] PURINES, INHIBITOR OF INFLAMMATORY CYTOKINES | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022864-A1 | 9-[(5-dihydroxyboryl)-pentyl] purines, useful as an inhibitor of inflammatory cytokines | IL1B, IL1A, IL1R1 | FDPS 222/4885LTA4H 638/4885HDAC1 3384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.