Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.46 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300729 | 0.87 | SLC22A12 (0.43) | PLAUSLC22A12PLA2G7SCN9ATRIM24 | |
| Trifluoroacetic Acid SCHEMBL7157237 | 0.85 | PLA2G7 (0.39) | PLAUSLC22A12PLA2G7SCN9AMEN1 | |
| Trifluoroacetic Acid SCHEMBL7155223 | 0.78 | PLA2G7 (0.43) | PLAUSLC22A12PLA2G7MEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL7150670 | 0.74 | PLA2G7 (0.41) | SLC22A12PLA2G7SCN9A | |
| SCHEMBL6295040 | 0.73 | BRD4 (0.43) | SLC22A12PLA2G7SCN9A | |
| Trifluoroacetic Acid SCHEMBL7153794 | 0.71 | BRD4 (0.40) | PLA2G7SCN9A | |
| Trifluoroacetic Acid SCHEMBL7150674 | 0.70 | PLA2G7 (0.37) | SLC22A12PLA2G7SCN9AMEN1MAPT | |
| Trifluoroacetic Acid SCHEMBL7150647 | 0.68 | PLA2G7 (0.44) | SLC22A12PLA2G7MEN1ALDH1A1LMNA | |
| Trifluoroacetic Acid SCHEMBL6300629 | 0.68 | PLA2G7 (0.44) | PLA2G7ALDH1A1LMNA | |
| SCHEMBL6300632 | 0.67 | PLA2G7 (0.43) | PLAUPLA2G7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916837-B2 | Amidino derivatives and anticoagulants and thrombosis therapeutic agents containing them | EISAI CO., LTD. (JP) | 2005-07-12 | — | — | US | disclosed |