Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB7A | P51149 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6321243 | 0.85 | ALDH1A1 (0.53) | SMN1; SMN2KDM4EHSD17B10ALDH1A1TP53 | |
| SCHEMBL7859642 | 0.83 | KDM4E (0.39) | SMN1; SMN2KDM4EHSD17B10ALDH1A1TP53 | |
| SCHEMBL6428209 | 0.83 | HPGD (0.54) | SMN1; SMN2KDM4EHSD17B10ALDH1A1TP53 | |
| SCHEMBL7159306 | 0.83 | HPGD (0.52) | SMN1; SMN2ALDH1A1POLBHPGDNPC1 | |
| SCHEMBL7860892 | 0.81 | SMYD3 (0.36) | SMN1; SMN2KDM4EHSD17B10ALDH1A1TP53 | |
| SCHEMBL7159868 | 0.81 | HPGD (0.47) | SMN1; SMN2KDM4EHSD17B10ALDH1A1TP53 | |
| SCHEMBL7855442 | 0.79 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1HPGDNPC1 | |
| SCHEMBL6400737 | 0.79 | RAB7A (0.37) | SMN1; SMN2HSD17B10ALDH1A1POLBTSHR | |
| SCHEMBL7162038 | 0.79 | MAPT (0.54) | TP53POLBRAB9AMAPT | |
| SCHEMBL7864273 | 0.78 | HPGD (0.41) | SMN1; SMN2KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | MOLLER NIELS PETER HUNDAHL (DK) | 2003-04-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPRCAP, PTPRS, PTPRA | SMN1; SMN2 1576/4885KDM4E 2352/4885HSD17B10 1518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.