Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860899 | 0.87 | ALDH1A1 (0.39) | HPGDKMT2AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL6205718 | 0.84 | KMT2A (0.49) | HPGDKMT2ASMN1; SMN2MEN1NOD1 | |
| SCHEMBL7155233 | 0.83 | SMN1; SMN2 (0.56) | HPGDKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6428209 | 0.82 | HPGD (0.54) | HPGDKMT2AL3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL7696900 | 0.81 | ALDH1A1 (0.49) | HPGDKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7860892 | 0.80 | SMYD3 (0.36) | HPGDKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7159868 | 0.80 | HPGD (0.47) | HPGDKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL7158445 | 0.79 | UBE2N (0.35) | HPGDKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL7855442 | 0.78 | KDM4E (0.55) | HPGDKMT2AALDH1A1RAB9AMAPT | |
| SCHEMBL6400737 | 0.77 | RAB7A (0.37) | HPGDKMT2AL3MBTL1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | MOLLER NIELS PETER HUNDAHL (DK) | 2003-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069267-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPRCAP, PTPRS, PTPRA | HPGD 2593/4885KMT2A 3329/4885L3MBTL1 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.