Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379811 | 0.90 | THRB (0.47) | THRBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL110982 | 0.82 | THRB (0.41) | THRBKDM4EPOLB | |
| SCHEMBL7177419 | 0.81 | THRB (0.39) | THRBNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11136454 | 0.80 | NPC1 (0.41) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL21586965 | 0.79 | NPC1 (0.40) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL6379807 | 0.78 | NPC1 (0.35) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL18280470 | 0.78 | KDM4E (0.35) | THRBKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8360557 | 0.78 | KDM4E (0.47) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL9417192 | 0.78 | NPC1 (0.36) | NPC1RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL19252768 | 0.78 | TDP1 (0.39) | NPC1RAB9AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1293541-A2 | Intraocular lens and dye therefor | Canon-Staar Co., Inc. (JP) | 2003-03-19 | — | — | EP | disclosed |