Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.31 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417231 | 0.92 | NPC1 (0.35) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL9467307 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1TDP1MAPTPPARA | |
| SCHEMBL19252768 | 0.88 | TDP1 (0.39) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL6902553 | 0.87 | ALOX5 (0.38) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL9417139 | 0.83 | NPC1 (0.45) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL21586965 | 0.82 | NPC1 (0.40) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL6379811 | 0.81 | THRB (0.47) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL11136454 | 0.81 | NPC1 (0.41) | NPC1RAB9AKDM4EALDH1A1TDP1 | |
| SCHEMBL107635 | 0.81 | POLB (0.36) | TDP1POLB | |
| SCHEMBL11441445 | 0.80 | NPC1 (0.39) | NPC1RAB9AKDM4EPOLBF2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475149-B1 | Coating composition and resin article coated thereby | NIPPON ARC CO LTD (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5250359-A | Weather resistant, abrasion resistant undercoatings | NIPPON ARC CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |