Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757071 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| 1,5-Pentanediol SCHEMBL5697406 | 0.98 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| 1,6-Hexanediol SCHEMBL7069312 | 0.98 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL6828621 | 0.98 | LMNA (0.55) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| Butyl Alcohol SCHEMBL28472879 | 0.93 | ALDH1A1 (0.52) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| Ethylene Glycol SCHEMBL8398487 | 0.92 | THRB (0.52) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| Propanol SCHEMBL27747409 | 0.92 | THRB (0.52) | SMN1; SMN2LMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL1934981 | 0.92 | — | — | |
| SCHEMBL53705 | 0.92 | — | — | |
| SCHEMBL2381705 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101821412-A | TOLL sample receptor modulators | IDERA PHARMACEUTICALS INC | 2010-09-01 | — | — | CN | disclosed |
| CN-101460178-A | Stabilized immune modulatory RNA (SIMRA) compounds for TLR7 and TLR8 | IDERA PHARMACEUTICALS INC (US) | 2009-06-17 | — | — | CN | disclosed |
| US-6541411-B2 | Reaction product of (condensed) orthoesters of titanium and/or zirconium and polyalcohol(s) in given molar ratio; hydrolysis resistance, nondiscoloring; preparing polyurethane foams | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |
| US-20020107143-A1 | Titanium/zirconium catalysts and their use to prepare esters or polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 2002-08-08 | — | — | US | disclosed |