SCHEMBL715592

SCHEMBL715592

CC(C)(C)c1c[c]cc(-n2nc3cccc(O)c3n2)c1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
PARP1 P09874 1/20 0.34
ACHE P22303 1/20 0.33
RAB9A P51151 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
POLB P06746 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8680274 0.75 CNR1 (0.40) HDAC4HDAC2HDAC8PARP1ACHE
SCHEMBL31398377 0.72 NPC1 (0.37) HDAC4HDAC2HDAC8ACHERAB9A
SCHEMBL460609 0.71 KDM4E (0.61) PARP1ACHERAB9ANPC1LMNA
SCHEMBL11545990 0.69 KDM4E (0.35) PARP1RAB9ANPC1LMNAPPARG
SCHEMBL6836243 0.67 KDM4E (0.48) PARP1RAB9ANPC1LMNAPPARG
SCHEMBL30648256 0.67 KDM4E (0.53) HDAC4HDAC2HDAC8PARP1RAB9A
SCHEMBL29145880 0.67 KDM4E (0.53) HDAC4HDAC2HDAC8PARP1RAB9A
SCHEMBL29692992 0.66 GABRA1 (0.47) RAB9ANPC1LMNAPPARGPPARA
SCHEMBL20404620 0.66 KDM4E (0.52) RAB9ANPC1LMNAPPARGPPARA
SCHEMBL28139129 0.65 POLB (0.62) PARP1ACHERAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166467-B Polyethylene or polypropylene articles 巴斯夫欧洲公司 2024-03-29 CN disclosed
CN-117677658-A Additive mixture for stabilizing organic materials 巴斯夫欧洲公司 2024-03-08 CN disclosed
CN-114616264-B Oligomer or polymer, composition, use of oligomer or polymer and intermediate 弗劳恩霍夫应用研究促进协会 2024-03-01 CN disclosed
CN-113348205-B Method for stabilizing halogen-free thermoplastic recyclates, plastic compositions, stabilizer compositions and use of stabilizer compositions 弗劳恩霍夫应用研究促进协会 2024-02-27 CN disclosed
CN-117355567-A Use of at least one sulfur-containing amino acid for stabilizing thermoplastic recycling material, stabilized thermoplastic recycling material, stabilizer composition, masterbatch and molding compound or molded part 弗劳恩霍夫应用研究促进协会 2024-01-05 CN disclosed
CN-117203271-A Use of a stabilizer composition for stabilizing halogen-free thermoplastic recycling material, a stabilizer composition, a masterbatch or concentrate, a stabilized plastic composition, a method for stabilizing halogen-free thermoplastic recycling material and use of a composition 弗劳恩霍夫应用研究促进协会 2023-12-08 CN disclosed
CN-117203272-A Stabilizer mixture 巴斯夫欧洲公司 2023-12-08 CN disclosed
CN-117015566-A Stabilizer composition, use of a stabilizer composition, method for stabilizing polycondensates against hydrolytic degradation, and hydrolytically stable compositions and mouldings or mouldings thereof 弗劳恩霍夫应用研究促进协会 2023-11-07 CN disclosed
CN-111051418-B Additive mixture 巴斯夫欧洲公司 2023-08-15 CN disclosed
CN-116583559-A Organic material-based molded article 巴斯夫欧洲公司 2023-08-11 CN disclosed
EP-1360177-A2 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME Cytec Technology Corp. (US) 2003-11-12 EP disclosed
CN-1437630-A Stabilizer mixture CIBA SC HOLDING AG (CH) 2003-08-20 CN disclosed
WO-2002059090-A2 OLIGOMERIC HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-08-01 WO disclosed
WO-2002057232-A2 HINDERED AMINE LIGHT STABILIZERS BASED ON MULTI-FUNCTIONAL CARBONYL COMPOUNDS AND METHODS OF MAKING SAME CYTEC TECHNOLOGY CORP. (US) 2002-07-25 WO disclosed
WO-2001023498-A1 METHOD FOR THE CONTINUOUS PRODUCTION OF STABILIZER DISPERSIONS BASF AKTIENGESELLSCHAFT (DE) 2001-04-05 WO disclosed
US-5574085-A TO PREVENT OXIDATIVE CROSSLINKING, STORAGE, STERICALLY HINDERED ALKYLTHIOALKYLPHENOL ESTERS CIBA-GEIGY CORPORATION (US) 1996-11-12 US disclosed
EP-0670843-A1 ALPHA CRYSTALLINE MODIFICATION OF 2,2',2\"-NITRILO TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE]. CIBA GEIGY AG (CH) 1995-09-13 EP disclosed
EP-0670842-A1 BETA CRYSTALLINE MODIFICATION OF 2,2',2''-NITRILO TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL) PHOSPHITE]. CIBA GEIGY AG (CH) 1995-09-13 EP disclosed
WO-1994012509-A1 ALPHA CRYSTALLINE MODIFICATION OF 2,2',2'-NITRILO[TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL)PHOSPHITE] CIBA-GEIGY AG (CH) 1994-06-09 WO disclosed
WO-1994012508-A1 BETA CRYSTALLINE MODIFICATION OF 2,2',2''-NITRILO[TRIETHYL-TRIS-(3,3',5,5'-TETRA-TERT-BUTYL-1,1'-BIPHENYL-2,2'-DIYL) PHOSPHITE] CIBA-GEIGY AG (CH) 1994-06-09 WO disclosed