SCHEMBL8680274

SCHEMBL8680274

CC(C)(c1ccccc1)c1cc(-n2nc3cccc(O)c3n2)cc(C(C)(C)c2ccccc2)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.40
CNR2 P34972 4/20 0.40
PARP1 P09874 1/20 0.40
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
ALDH1A1 P00352 3/20 0.38
CYP3A4 P08684 1/20 0.38
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
POLB P06746 1/20 0.34
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6445924 0.84 KDM4E (0.52) CNR1CNR2ESR1ESR2PPARG
SCHEMBL3680277 0.84 PPARG (0.41) CNR1CNR2ESR1ESR2PPARG
SCHEMBL29351747 0.84 PPARG (0.41) CNR1CNR2ESR1ESR2PPARG
SCHEMBL460609 0.78 KDM4E (0.61) PARP1ALDH1A1KDM4EHPGDRAB9A
SCHEMBL5561249 0.75 PPARG (0.41) CNR1CNR2ESR1ESR2PPARG
SCHEMBL715592 0.75 HDAC4 (0.34) PARP1PPARGPPARAALDH1A1RAB9A
SCHEMBL22271031 0.75 KDM4E (0.41) CNR1CNR2ESR1ESR2PPARG
SCHEMBL4159028 0.73 PPARG (0.46) CNR1CNR2ESR1ESR2PPARG
SCHEMBL1526132 0.73 KDM4E (0.50) PARP1ESR1ESR2PPARGPPARA
SCHEMBL6028192 0.73 NPC1 (0.56) CNR1CNR2ESR1ESR2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8618191-B2 Acrylic based resin composition and molded product using the same CHEIL INDUSTRIES INC. (KR) 2013-12-31 US claimed
US-20120172499-A1 Acrylic Based Resin Composition and Molded Product Using the Same CHEIL INDUSTRIES INC. (KR) 2012-07-05 US claimed
US-5744273-A Laminatable backing substrates containing fluoro compounds for improved toner flow XEROX CORPORATION (US) 1998-04-28 US disclosed